Hiroko Imasato

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Our goal is development of a new automatic blood cell counter that it can detect a small amount of leukemia cells in the blood of patients. We employ the dielectrophoresis (DEP). In this paper, we examine whether or not realization that a living blood cells are separated by employing the dielectrophoresis. Leukocyte and erythrocyte are separated by(More)
In this study, we present the methods of the particle separation by employing electrokinetic phenomena (dielectrophoresis (DEP) and traveling-wave electroosmosis (TWEO)) and the inclined gravity. The methods can separate particles of same sign DEP. However, it is very difficult to separate particles on a plane electrode. To cope with this problem, we create(More)
In this paper, we present the methods of the particle separation by employing dielectrophoresis (DEP) and traveling-wave electroosmosis (TWEO). When particles are on a plane electrode, the particles do not experience the DEP force. Because the electric field at surface of the plane electrode is zero. Thus it is necessary to transport all particles from the(More)
If the nuclear folding and clefting characteristic of monocytoid cells are not present, the morphologic features observed under light microscopy may not be sufficient to clarify the diagnosis. Much more reliable methodology should be developed for the clinical examination. Dielectrophoresis (DEP) is the motion of a matter caused by polarization effects in a(More)
Dielectrophoresis (DEP) is the motion of a matter caused by polarization effects in a non-uniform electric field. We have been studying to measure dielectrophretic force (DEP force) generated on a small particle by equipment which we developed [1][2][3]. For calculating the DEP force, the mass density of the target particle in the DEP device is necessary.(More)
Under travelling-wave electric fields, particles are propelled along an electrode array by the travelling-wave dielectrophoresis and the travelling-wave electroosmotic fluid flow. In the low frequency range, the horizontal movement of particles is dominated by the travelling-wave electroosmotic fluid flow. The fluid flow depends on the geometry of the(More)
Electrorotation is a noninvasive technique to measure the dielectric properties of biological cells. In this paper, We fabricate an electrorotation microwell array for high-throughput dielectric characterization of circulating tumor cells (CTCs). The device consists of a microwell array and electrorotation chip. The practicality of the device was evaluated(More)
Dielctrophoresis (DEP) is a movement of particles in medium by a force, which is generated in non-uniform electric fields. The Dielectrophoretic force (DEP force) depends on the geometry of an electrode. In this paper, the design and the simulation of the ceiling electrode to separate biological cells by using positive dielectrophoresis and inclined gravity(More)
The dielectrophoresis (DEP) is suitable for handling micro-/nano-particles or tubes, sometimes together with gravity and/or flow of liquids. Recently research works on applications of DEP to biochemical measurement of biological cells alive or dead. Mass-processing of clinical laboratory test will be led to Clinical Laboratory Automation. We made(More)
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