Hirokazu Tsubone

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The authors studied power spectral analysis of heart rate variability in the rat, hypothesizing that the quantitative information provided by this analysis reflects the interaction between sympathetic and parasympathetic regulatory activities. For this purpose, an electrocardiogram was recorded from conscious and unrestrained Wistar rats (Nippon, Shizuoka)(More)
BACKGROUND AND PURPOSES The purpose of the study was to document diurnal variation of autonomic nervous functions by use of power spectral analysis of heart rate (HR) variability. METHODS To clarify characteristics of power spectral analysis of HR variability, electrocardiogram (ECG), blood pressure (BP), and respiratory (Resp) waveform simultaneously(More)
To clarify the toxic effects of diesel exhaust (DE) on delivery in mice and on growth of young, C57Bl-strain females were exposed to 0.3, 1.0, or 3.0 mg diesel exhaust particles (DEP)/m3 or filtered clean air (control) for 4 mo (12 h/day, 7 days/wk). After exposure, some females from each group were examined by necropsy, and the remainders were mated with(More)
We investigated the role of cysteinyl leukotriene (CysLT) receptors on leukotriene D(4)-induced actin reorganization and the signaling pathways of the response in human bronchial smooth muscle cells. The effects of leukotriene D(4) on actin reorganization in human bronchial smooth muscle cells were evaluated by dual-fluorescence labeling of filamentous (F)(More)
We studied power spectral analysis of heart rate (HR) variability in the horse, with the hypothesis that the quantitative information provided by the spectral analysis of HR variability reflects the interaction between sympathetic and parasympathetic regulatory activities. For this purpose, electrocardiogram, blood pressure (BP) and respiratory (Resp)(More)
The responses of laryngeal capsaicin (CAPS)-sensitive receptors to halothane, enflurane, isoflurane and sevoflurane were evaluated in anesthetized spontaneously breathing dogs from the afferent activity of the internal branch of the superior laryngeal nerve. The CAPS-sensitive receptors were clearly distinguished from irritant receptors by their(More)
We studied the diurnal variations of autonomic nervous function in rats. For this purpose, a long-term electrocardiogram (ECG) was recorded from conscious and unrestrained rats using a telemetry system, and the autonomic nervous function was investigated by the power spectral analysis of heart rate variability. No arrhythmias were observed in the ECG of any(More)
This study investigated the effects of pair housing on diurnal rhythms of heart rate and autonomic nervous activity in miniature swine. For this purpose, six adult Göttingen miniature swine were initially housed individually in an animal cage. Then, two of each swine were housed in a large cage together for 3 weeks. After that swine were separated into(More)
We have studied the physiological and behavioural responses in small rodents to ambient alterations. For this purpose, voles and mice were exposed to relatively low (12 degrees C) and high (35 degrees C) ambient temperatures, and heart rate (HR), locomotor activity (LA) and body temperature (BT) were recorded using telemetry system. The control HR (at 24(More)
OBJECTIVE To determine the effects of initial handling and training on autonomic nervous functions in young Thoroughbreds. ANIMALS 63 healthy Thoroughbreds. PROCEDURE All horses were trained to be handled and initially ridden in September of the yearling year and then trained until the following April by conventional training regimens. To obtain the(More)