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Human transferrin (Tf) very tightly binds two ferric ions to deliver iron to cells. Fe(III)2Tf (Fe2Tf) binds to the Tf receptor (TfR) at pH 7.4; however, iron-free Tf (apoTf) does not. Iron uptake is(More)
Tenascin-C is an adhesion modulatory matrix protein that is highly expressed in tumors; however, its biochemical activity involved in tumorigenesis is not fully understood. On the other hand,(More)