Hirofumi Niwamoto

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Hepatitis B virus is associated with humanhepatocellular carcinoma. We performed polymerase chainreaction for the X, C, S, and preS2/S regions of theviral genome in 23 hepatitis B surface antigen-negative hepatocellular carcinomas and adjacent liver.Hepatitis B viral genomes were detected in 17 of 23tumors and adjacent tissues (73.9%). Among(More)
We encountered three cases of chronic functional colonic obstruction caused by intramural ganglion cell death. Morphologic and pharmacological studies were performed using resected specimens. The patients included a 59-year-old man, a 72-year-old woman, and a 28-year-old man. Barium enema studies revealed segmental stenosis in their left colon. A mecholyl(More)
The disturbance of defecation in the patient with Hirschsprung's disease and the pathophysiology of constipation in the constipated patient with simple megarectum were investigated. In Hirschsprung's disease, an existence of aganglionosis and the sphincter achalasia are two main factors which cause clinical symptoms such as chronic constipation and(More)
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