Hinrich Rahmann

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The data presented support the idea that gangliosides are involved in thermal adaptation of neuronal membranes. Brain ganglioside patterns from cold-blooded vertebrate species living in different climates and from mammals during ontogenetical or seasonal changes in their body temperature were compared. The general rule "the lower the environmental(More)
1. The effects of Pb2+ and Zn2+ on the peak of the voltage-activated calcium current of Aplysia neurons were examined. Calcium currents were reversibly blocked by Pb2+ at concentrations that did not significantly affect potassium and sodium currents and by Zn2+ at concentrations associated with a delay and reduction of peak sodium and potassium currents. 2.(More)
Using conventional two electrode voltage clamp techniques we have studied the effects of Pb2+, triethyl lead (TEL) and Hg2+ on voltage-activated calcium channels of Aplysia neurons and found that all three metals are potent inhibitors at micromolar concentrations. However, the time course of current reduction or block and its reversibility vary when(More)
To confirm the effect of gangliosides on the facilitation of the induction of long-term potentiation (LTP), slices of hippocampus and superior colliculus from guinea pig were prepared. One group of slices was incubated in the standard medium containing gangliosides (GM1, GD1a, or a mixture of gangliosides from bovine brain, each at a concentration of 70(More)
Polysialic acid on the neural cell adhesion molecule is developmentally regulated and has been implicated in the plasticity of cell-cell interactions. The sialyltransferases ST8Sia II and ST8Sia IV are able to catalyze the synthesis of polysialic acid. This study compares the expression of ST8Sia II and ST8Sia IV mRNA during postnatal rat brain development.(More)
The distribution of nicotinamide adenine dinucleotide phosphate-diaphorase (or -dehydrogenase, NADPHDH, a marker for nitric oxide synthase, NOS) positive neurons was demonstrated histochemically in the central nervous system of the swordtail fish Xiphophorus helleri, a highly derived telost of the atherinomorph outgroup. All nuclei of the swordtail fish,(More)
1. The functional properties of biological membranes depend on their molecular composition. In regard to this, charged glycosphingolipids play an outstanding role in the functional adaptation of membranes to different temperatures. 2. In order to shed some light on the respective functional properties of complex membraneous glycosphingolipids, the effects(More)
Size and asymmetry (size difference between the left and right sides) of inner ear otoliths of larval cichlid fish were determined after a long-term stay in moderate hypergravity conditions (3g; centrifuge), in the course of which the animals completed their ontogenetic development from hatch to freely swimming. Neither the normal morphogenetic development(More)
Using the GD3-specific mAb R24 we demonstrate by immunohistochemistry that the first embryonic cells of chicken expressing GD3 represent heavily proliferating cells of mesodermal origin (mesenchymal stem and endothelial cells). At this developmental stage (E1-1.5) neuroectodermal cells of the forming neural tube are not stained by R24 or any other available(More)