BACKGROUND An estimated 350 adults develop severe, but potentially reversible respiratory failure in the UK annually. Current management uses intermittent positive pressure ventilation, but barotrauma, volutrauma and oxygen toxicity can prevent lung recovery. An alternative treatment, extracorporeal membrane oxygenation, uses cardio-pulmonary bypass… (More)
Little is known about the mechanical forces acting on extracorporeal circuit tubing with prolonged roller pump use during extracorporeal membrane oxygenation (ECMO). We examined the time to tubing rupture of three different materials during actual roller pump use, mean and standard deviation (SD) (SD shown in parentheses): Tygon (control) 243.7 h (175.4);… (More)
Reinnervation of transplanted muscles occurs in 2 steps. During the first 5 months the motor axon terminals innervate primarily the border of the original endplate zone, re-establishing its previous outline. In the next 4 months, by further ramifying of the axons, new nerve-muscle contacts are formed exclusively within the boundaries of this zone.