Hillary L. Woodworth

Learn More
Neurons of the lateral hypothalamic area (LHA) control motivated behaviors such as feeding and ambulatory activity, in part by modulating mesolimbic dopamine (DA) circuits. The hormone, leptin, acts via the long form of the leptin receptor (LepRb) in the brain to signal the repletion of body energy stores, thereby decreasing feeding and promoting activity.(More)
Survival depends on an organism's ability to sense nutrient status and accordingly regulate intake and energy expenditure behaviors. Uncoupling of energy sensing and behavior, however, underlies energy balance disorders such as anorexia or obesity. The hypothalamus regulates energy balance, and in particular the lateral hypothalamic area (LHA) is poised to(More)
Hormones, growth factors and cytokines produced by adipocytes are associated with cancer progression. We suggest that chronically elevated adipokines as observed in the obese state may have profound effects locally on colon epithelial cells through growth promotion effects, induction of autocrine signaling, angiogenesis and immune cross-talk. This(More)
OBJECTIVE Children of parents with major depression are at significantly increased risk for developing major depression themselves; however, not all children at genetic risk will develop major depressive disorder (MDD). We investigated the utility of subsyndromal scores on the Child Behavior Checklist (CBCL) Anxiety/Depression scale in identifying children(More)
  • 1