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  • Sylvie Bertholet, Gregory C. Ireton, +9 authors Steven G Reed
  • Medicine
  • Science Translational Medicine
  • 2010 (First Publication: 13 October 2010)
  • A vaccine with a four-protein fusion peptide from Mycobacterium tuberculosis effectively boosts the current childhood TB vaccine and protects against drug-resistant TB. A Superior Shot forContinue Reading
  • Mauricio Aguayo Arias, Griet A Van Roey, +6 authors Robin J Shattock
  • Chemistry, Medicine
  • PloS one
  • 2012 (First Publication: 19 July 2012)
  • Successful vaccine development against HIV will likely require the induction of strong, long-lasting humoral and cellular immune responses in both the systemic and mucosal compartments. Based on theContinue Reading
  • Hillarie Plessner Windish, Philana Ling Lin, +4 authors JoAnne L. Flynn
  • Biology, Medicine
  • Journal of leukocyte biology
  • 2009 (First Publication: 1 September 2009)
  • Foxp3+ T regulatory cells are required to prevent autoimmune disease, but also prevent clearance of some chronic infections. While natural T regulatory cells are produced in the thymus, TGF-beta1Continue Reading
  • Mark T Orr, Malcolm S Duthie, +8 authors Rhea N Coler
  • Biology, Medicine
  • European journal of immunology
  • 2013 (First Publication: 1 September 2013)
  • Glucopyranosyl lipid adjuvant-stable emulsion (GLA-SE) is a synthetic adjuvant TLR4 agonist that promotes potent poly-functional T(H)1 responses. Different TLR4 agonists may preferentially signal viaContinue Reading