Hilde M. Huizenga

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In the standard Iowa Gambling Task (IGT), participants have to choose repeatedly from four options. Each option is characterized by a constant gain, and by the frequency and amount of a probabilistic loss. Crone and van der Molen (2004) reported that school-aged children and even adolescents show marked deficits in IGT performance. In this study, we have(More)
PURPOSE To evaluate the influence of adjuvant tamoxifen and exemestane on cognitive functioning in postmenopausal patients with breast cancer (BC). PATIENTS AND METHODS Neuropsychological assessments were performed before the start (T1) and after 1 year of adjuvant endocrine treatment (T2) in Dutch postmenopausal patients with BC, who did not receive(More)
Scores on cognitive tasks used in intelligence tests correlate positively with each other, that is, they display a positive manifold of correlations. The positive manifold is often explained by positing a dominant latent variable, the g factor, associated with a single quantitative cognitive or biological process or capacity. In this article, a new(More)
A method is described to incorporate the spatiotemporal noise covariance matrix into a spatiotemporal source analysis. The essential feature is that the estimation problem is split into two parts. First, a model is fitted to the observed noise covariance matrix. This model is a Kronecker product of a spatial and a temporal matrix. The spatial matrix models(More)
A method is described to derive source and conductivity estimates in a simultaneous MEG and EEG source analysis. In addition the covariance matrix of the estimates is derived. Simulation studies with a concentric spheres model and a more realistic boundary element model indicate that this method has several advantages, even if only a few EEG sensors are(More)
Random effects meta-regression is a technique to synthesize results of multiple studies. It allows for a test of an overall effect, as well as for tests of effects of study characteristics, that is, (discrete or continuous) moderator effects. We describe various procedures to test moderator effects: the z, t, likelihood ratio (LR), Bartlett-corrected LR(More)
The source of an event related brain potential (ERP) is estimated from multivariate measurements of this ERP on the head under several mathematical and physical constraints on the parameters of the source model. We will discuss statistical aspects of standard methods to estimate these parameters and their confidence intervals. In addition new principled(More)
The general spatiotemporal covariance matrix of the background noise in MEG/EEG signals is huge. To reduce the dimensionality of this matrix it is modeled as a Kronecker product of a spatial and a temporal covariance matrix. When the number of time samples is larger than, say, J = 500, the iterative Maximum Likelihood estimation of these two matrices is(More)
BACKGROUND The ability to inhibit motor responses, as assessed by the stop-signal reaction time (SSRT), is impaired in children and adolescents with attention-deficit/hyperactivity disorder (ADHD). However, the between-study variation in effect sizes is large. The aim of this study was to investigate whether this variability can be explained by(More)