Hilde Bosmans

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PURPOSE This work proposes a new method of building 3D models of microcalcification clusters and describes the validation of their realistic appearance when simulated into 2D digital mammograms and into breast tomosynthesis images. METHODS A micro-CT unit was used to scan 23 breast biopsy specimens of microcalcification clusters with malignant and benign(More)
PURPOSE From independently conducted free-response receiver operating characteristic (FROC) and receiver operating characteristic (ROC) experiments, to study fixed-reader associations between three estimators: the area under the alternative FROC (AFROC) curve computed from FROC data, the area under the ROC curve computed from FROC highest rating data, and(More)
Planar 2D X-ray mammography is the most common screening technique used for breast cancer detection. Digital breast tomosynthesis (DBT) is a new and emerging technology that overcomes some of the limitations of conventional planar imaging. However, it is important to understand the impact of these two modalities on cancer detection rates and patient recall.(More)
Accurate reconstruction of SPECT images is hampered by four nonlinear effects in the acquisition process: attenuation, scatter, collimator acceptance angle, and statistical noise. A good mathematical description of these effects is obviously crucial for the reconstruction. Poisson noise, attenuation, and collimator acceptance angle are relatively easy to(More)