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Different types of ellagitannins are reported to have various biological activities, such as antioxidant, antiviral, and antitumor activities. However, there are few definitive studies on the absorption and metabolism of ellagitannins. This review compares the absorption and metabolism of ellagitannins, and the antioxidant properties of their metabolites in(More)
We evaluated the neurotrophic activity of dietary polyphenols by using primary cultures of fetal rat hippocampal neurons in a serum-free medium. Among the tested compounds, chlorogenic acid and its metabolite, m-coumaric acid, together with catechins and flavanone, were found to promote neuronal differentiation comparable to the phytochemical, honokiol,(More)
This paper presents an automatic tuning method of model predictive control (MPC) using particle swarm optimization (PSO). Although it is difficult for unskilled control designers to tune MPC weight parameters, PSO can solve this issues and practical control can be realized in various industrial problems. One of the challenges in MPC is how control(More)
PCA realizes parallel computing with objects and message passing by using this dual structure (Fig.1). An object is a logic circuit or a memory block configured on the PP-plane; Abstract This paper describes the realization of a dynamically reconfigurable logic LSI based on a novel parallel computer architecture. The key point of the architecture is its(More)
BACKGROUND Left ventricular (LV) remodeling leads to chronic heart failure and is a main determinant of morbidity and mortality after myocardial infarction (MI). At the present time, therapeutic options to prevent LV remodeling are limited. METHODS AND RESULTS We created a large MI by permanent ligation of the coronary artery and identified a potential(More)
Cranberry, which is rich in polyphenols, including anthocyanins and proanthocyanidins, has been found to have various effects beneficial to human health, including prevention of urinary tract infections. These effects have been associated with polyphenols in the fruit. We investigated the excretion of anthocyanins in human urine after ingestion of cranberry(More)
1.1 Old and New Concepts of Tannins The pharmacological activities of tannins described in medicinal books before the recent achievements on ellagitannin chemistry were mostly those of gallotannins and condensed tannins of poor chemical uniformity. The gallotannins extracted from Chinese or Turkish gall, sometimes called tannic acid, are variable mixtures(More)