Hidetomo Niwa

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Neuropeptide S (NPS) is an endogenous peptide that exerts wakefulness promoting, analgesic, and anxiolytic effects when administered exogenously. However, it remains to be determined if endogenous NPS tone is involved in the control of the diurnal sleep-wake cycle, or spontanous behavior. In this study, we examined the effects of the NPS receptor antagonist(More)
A power spectral analysis of electroencephalograms (EEGs) was performed in 30 infants who underwent plastic surgery for cleft lip or cleft palate. The study was conducted to investigate whether there was a significant correlation between EEG changes and arterial halothane concentration in infants. The power spectral analysis of EEGs was performed by the(More)
BACKGROUND Anesthesia and surgery disturb sleep. Disturbed sleep adversely affects postoperative complications involving the cardiovascular system, diabetes, and infection. General anesthetics share neuronal mechanisms involving endogenous sleep-wakefulness-related substances, such as orexin (OX) and melanin-concentrating hormone (MCH). We evaluated changes(More)
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