Hideto Oshita

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UNLABELLED Genome-wide gene expression profiling revealed that the Ras and EF-hand domain containing (RASEF) transcript was significantly transactivated in the majority of lung cancers. Using lung cancer cells, transient expression of RASEF promoted cell growth, whereas RASEF knockdown not only reduced its expression but resulted in growth suppression of(More)
Purpose: This study aims to identifymolecules thatmight be useful as diagnostic/prognostic biomarkers and as targets for the development of new molecular therapies for lung cancer. Experimental Design:We screened for genes that were highly transactivated in a large proportion of 120 lung cancers bymeans of a cDNAmicroarray representing 27,648 genes and(More)
PURPOSE This study aims to identify novel biomarkers and therapeutic targets for lung cancer. EXPERIMENTAL DESIGN We carried out gene expression profile analysis of 120 lung cancers to screen for genes encoding transmembrane/secretory molecules that are commonly transactivated in lung cancers. Epstein-Barr virus-induced gene 3 (EBI3), which encodes a(More)
PURPOSE This study aims to identify molecules that might be useful as diagnostic/prognostic biomarkers and as targets for the development of new molecular therapies for lung cancer. EXPERIMENTAL DESIGN We screened for genes that were highly transactivated in a large proportion of 120 lung cancers by means of a cDNA microarray representing 27,648 genes and(More)
Genome-wide gene expression profiling revealed that the Ras and EF-hand domain containing (RASEF) transcript was significantly transactivated in the majority of lung cancers. Using lung cancer cells, transient expression of RASEF promoted cell growth, whereas RASEF knockdown not only reduced its expression but resulted in growth suppression of the cancer(More)
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