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We have previously demonstrated that stimulation of the angiotensin (Ang) II type 2 receptor in vascular smooth muscle cells caused bradykinin production by activating kininogenase in transgenic mice. The aim of this study was to determine whether overexpression of AT2 receptors in cardiomyocytes attenuates Ang II-induced cardiomyocyte hypertrophy or(More)
To compare the feasibility of response scales with different numbers of steps for measuring health status, we assessed the ease of completing 4, 5, and 7-point scales and a visual analog scale. Four forms of the questionnaire, each of which consisted of the same ten questions about health status, but with a different type of scale among the four above(More)
BACKGROUND Metabolic syndrome has become a major worldwide public health problem. We examined the relationship between coffee consumption and the prevalence of metabolic syndrome among Japanese civil servants. METHODS The study participants were 3284 employees (2335 men and 948 women) aged 20 to 65 years. Using data from their 2008 health checkup records,(More)