Hideo Kusuoka

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We examined the effect of cardioprotective agents on three distinct phases of the H2O2-induced response that leads to loss of mitochondrial membrane potential (DeltaPsi(m)) and cell death in cultured cardiac myocytes: (1) priming, consisting of calcium-dependent morphological changes in mitochondria (swelling and loss of cristae), with preserved(More)
BACKGROUND Quality management in health care services has not been as successful as in other industries. OBJECTIVE To assess the potential contribution of an on-line incident reporting system (OIRS) and of an electronic patient record (EPR) system to quality management in hospitals. METHODS The two approaches are being implemented in Osaka University(More)
OBJECTIVE Individuals with type 2 diabetes are at high risk for cardiovascular events. We evaluated the prognostic value of gated myocardial perfusion single-photon computed tomography (SPECT) for asymptomatic diabetic patients in a Japanese population. RESEARCH DESIGN AND METHODS Asymptomatic patients (n=485) aged≥50 years with either a maximal carotid(More)
To enhance medical cooperation between the hospitals and clinics around Osaka local area, the healthcare network system, named Osaka Community Healthcare Information System (OCHIS), was established with support of a supplementary budget from the Japanese government in fiscal year 2002. Although the system has been based on healthcare public key(More)
OBJECTIVES To evaluate the short-term and long-term prognostic impacts of acute phase coronary collaterals to occluded infarct-related arteries (IRA) after ST-elevation myocardial infarction (STEMI) in the percutaneous coronary intervention (PCI) era. DESIGN A prospective observational study. SETTING Osaka Acute Coronary Insufficiency Study (OACIS) in(More)
INTRODUCTION International norms and ethical standards have suggested that compensation for research-related injury should be provided to injured research volunteers. However, statistical data of incidence of compensation claims and the rate of awarding them have been rarely reported. METHOD Questionnaire surveys were sent to pharmaceutical companies and(More)
To share healthcare information and to promote cooperation among healthcare providers and customers (patients) under computerized network environment, a non-profit organization (NPO), named as OCHIS, was established at Osaka, Japan in 2003. Since security and confidentiality issues on the Internet have been major concerns in the OCHIS, the system has been(More)
We proposed a suitable method to search similar cases from the laboratory test results database, whose data are basically numerical and ordinal data. We transformed raw data into ordinal ranks and into new scores lying between 0 and 1, then calculated the Mahalanobis distances as a similarity measure. We used 3000 cases of blood count data. In 100 sample(More)
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