Hideo Hirayama

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BACKGROUND AND OBJECTIVES Intravenous myocardial contrast echocardiography is used clinically, but use in small animals has not been evaluated. The conditions for myocardial opacification and the feasibility of myocardial contrast echocardiography were examined in mice. METHODS Closed chest mice were examined. The left ventricular short-axis view at the(More)
Angiogenesis is under intense investigation to advance the treatment of various ischemic diseases. Small animals, such as mice and rats, are often used for this purpose. However, evaluating the structure of coronary arteries in small animals in situ is not easy. We succeeded in visualizing the coronary artery in rats on 3-dimensional real-time contrast(More)
Secondary hyperparathyroidism (II HPT) is a major complication in chronic dialysis patients, and percutaneous ethanol injection therapy (PEIT) has become a useful alternative treatment for II HPT. However, the existence of ectopic parathyroid glands is a major problem when conducting PEIT. Ectopic parathyroid gland accepts 10-35% of II HPT, and the missing(More)
Hyperhomocysteinemia, a well-recognized cardiovascular risk factor, is frequent in hemodialysis (HD) patients. A common polymorphism in the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene, C-->T substitution at nucleotide 677, is associated with homocysteine (Hcy) level elevation. We examined whether three factors involved in the methionine cycle(More)
The effect of ultrasound signal attenuation on myocardial blood flow parameters derived from contrast replenishment was evaluated using harmonic gray-scale (HGS) and harmonic power Doppler (HPD) imaging. In vitro experiments were performed in a flow model, whereas in vivo experiments were performed in 5 open-chest dogs. In each study, intermittent HGS and(More)
  • H Hirayama
  • [Hokkaido igaku zasshi] The Hokkaido journal of…
  • 1985
Experiments were performed on cats with chronic spinal lesions, in order to decide which systems either interlimb-propriospinal systems or direct descending systems, plays important roles for coordination of overground locomotion of the cat. The phase relationships between homolateral, crossed, bilateral forelimbs and hindlimbs were analysed during(More)
OBJECTIVE This study was established to examine the efficacy of a high-frequency liner probe for visualizing fine anatomy of coronary microcirculation. METHODS The vessel size and its velocity-time integral at the anterior wall in dogs by real-time contrast echocardiography with high-frequency liner probe and pulse Doppler methods, and the coronary flow(More)
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