In this article, I have thoroughly reviewed the status of development of new antimycobacterial drugs, in particular, rifamycin derivatives (rifabutin, rifapentine, and a new benzoxazinorifamycin, KRM-1648), fluoroquinolones (ciprofloxacin, ofloxacin, sparfloxacin, levofloxacin, gatifloxacin, sitafloxacin, moxifloxacin, and others), new macrolides… (More)
Little is known about the correlation between genotype and drug susceptibility in Mycobacterium avium (Mav) strains isolated from patients with Mav infections. To examine whether drug susceptibility profile of Mav is associated with genotype, we carried out variable-number tandem-repeat (VNTR) typing and drug susceptibility testing for Mav isolates from… (More)
A method for hand-assisted laparoscopic construction of gastric conduit for thoracic esophageal cancer was developed. Since this endoscopic surgical procedure is less invasive than open surgery, it contributes to improvement of post-operative respiratory functions and reduces respiratory complications. What distinguishes our surgical procedure is that… (More)
A very rare case of eosinophilic granulocytosis of the cerebrospinal fluid (CSF eosinophilia) due to drug allergy caused by the intraventricular administration of gentamicin sulfate is presented with a review of the pertinent literature. An unusual clinical course and clinicoimmunological examination are also described.
We have described photic driving evoked by hemifield 5/sec flickering dot pattern stimulation in a patient suffering from a metastatic tumor in the left parietal lobe. Based on an analysis of the photic driving in this particular patient, the left upper lip of the visual cortex is presumed to be the most sensitive to 5/sec flickering dot pattern… (More)