Hidenori Matsunaga

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There is a hypothesis that autoimmune abnormalities in neurotransmitter receptors might cause some psychiatric disorders. Using a sensitive radioligand assay, we detected serum autoantibodies to recombinant human muscarinic cholinergic receptor 1 (CHRM1, 34.4%), mu-opioid receptor (OPRM1, 13.1%), 5-hydroxytryptamine receptor 1A (HTR1A, 7.4%), and dopamine(More)
OBJECTIVE The aim of the present study was to determine the efficacy of ramelteon for treating delirium. METHODS Three patients were prescribed ramelteon for delirium. The severity of the delirium was assessed using the Japanese version of the Memorial Delirium Assessment Scale. RESULTS Memorial Delirium Assessment Scale scores improved after treatment(More)
OBJECTIVE To identify of the gene responsible for the onset of spinocerebellar ataxia type 16 (SCA16). METHODS We reanalyzed the linkage of the original Japanese pedigree using updated information, including three additional subjects. We then screened all exons located in the critical region. RESULTS We reassigned the locus of SCA16 to 3p26.2-pter(More)
OBJECTIVE Memantine has been reported to have positive effects on visual hallucinations and cognition in patients with dementia with Lewy bodies (DLB). We hypothesized that memantine would have similar effects on a patient having Charles Bonnet syndrome, preclinical DLB. METHOD We evaluated the effect of memantine on visual hallucination, cognitive(More)
OBJECTIVE To highlight the association between posterior reversible encephalopathy syndrome (PRES) and chronic alcoholism. METHODS We present a case report, a review of the literature and a discussion. RESULTS We report on the case of a 51-year-old man with chronic alcoholism, who suddenly developed visual disturbance and confusion. Magnetic resonance(More)
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