Hideko Sawada

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PURPOSE To investigate the concentration of tumor necrosis factor (TNF)-alpha in the aqueous humor of patients with glaucoma, including correlations with glaucoma subtypes and intraocular pressure. METHODS The study population comprised 84 patients with open-angle glaucoma who were scheduled for filtration or cataract surgery. Glaucoma subgroups included(More)
PURPOSE The purpose of this study was to analyze the relationship between the mean deviation (MD) slope as the progressive rate of visual field defects and the follow-up intraocular pressure (IOP) in open-angle glaucoma (OAG) patients. METHODS This study was a retrospective, nonrandomized comparative study. A total of 287 eyes from 287 Japanese OAG(More)
PURPOSE To evaluate the correlation between quality of vision (QOV) and visual function in glaucoma patients. PATIENTS AND METHODS The relationship between QOV and visual function was investigated in 200 Japanese glaucoma patients. QOV was assessed using the Japanese version of the 25-item National Eye Institute Visual Function Questionnaire. The better(More)
PURPOSE To evaluate the incidence, severity, and factors related to drug-induced keratoepitheliopathy in eyes using antiglaucoma eye drops. PATIENTS AND METHODS In a cross-sectional study, 749 eyes from 427 patients who had used one or more antiglaucoma eye drops were examined at Niigata University Medical and Dental Hospital or related facilities. The(More)
PURPOSE Latanoprost 0.005%/timolol maleate 0.5% combination eye drops are now available in Japan. The aim of the present study was to investigate the prospective intraocular pressure (IOP) reduction effects and adherence with the combination eye drops in Japanese patients. METHODS The subjects were 162 patients (162 eyes) with glaucoma or ocular(More)
We compared two types of visual field index including mean deviation (MD) and the visual field index (VFI) for assessing the relationship between quality of life (QOL) and the loss of visual field in open-angle glaucoma patients. We examined 336 eyes of 168 consecutive glaucoma patients. All participants completed the Japanese version of the 25-item(More)
PURPOSE To investigate retrospectively the visual course for proliferative diabetic retinopathy after pars plana vitrectomy. CASES AND METHODS From January 2002 to December 2004, we operated 209 eyes with proliferative diabetic retinopathy. For this study, we selected 28 eyes in which the visual acuity could be followed for 6 months or longer after the(More)
PURPOSE To investigate the levels of oxidative stress markers in human eyes with senile cataracts. METHODS We conducted a retrospective, case-controlled study of 57 patients with senile cataracts. To assess oxidative stress markers in the eye, we measured the enzymatic activities of superoxide dismutase (SOD) and catalase (CAT) as well as the total(More)
To examine the composition of scleral sulfated proteoglycans in three nanophthalmic eyes by electron microscopic histochemistry. Scleral tissues from three cases of nanophthalmos were collected from the Niigata University Hospital for transmission electron microscopic examination. Sulfated proteoglycans were studied using the cuprolinic blue (CB) dye(More)
BACKGROUND We report a patient with acute angle-closure glaucoma secondary to annular ciliochoroidal detachment after unsutured cataract surgery. CASE An 82-year-old man was diagnosed with bilateral shallow central anterior chamber depth, flat peripheral anterior chamber, and elevated intraocular pressure. One day previously he had undergone uncomplicated(More)