Herton Fenner

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The role of cytokines in inflammatory joint diseases is well documented, especially with regard to tissue destruction and remodelling. In these processes, IL-1 and TNF alpha play a prominent part by stimulating protease production. The regulation of their production, their release and their effects on target cells (e.g. synovial cells, chondrocytes and(More)
Blood binding of tenoxicam was studied in vitro by equilibrium dialysis. Isolated human plasma proteins and blood cells were checked, and the distribution of the bound form was then calculated. The results showed that tenoxicam is mainly bound to HSA and that binding percentages are not different when measured in plasma (98.4%) and in an HSA solution at(More)
In the title complex, [Au(C(12)H(8)N(5)O(4))(C(18)H(15)P)], the coordination geometry about the Au(I) ion is linear, with one deprotonated 1,3-bis(4-nitrophenyl)triazenide ion, [O(2)NC(6)H(4)N=N-NC(6)H(4)NO(2)](-), acting as a monodentate ligand (two-electron donor), and one neutral triphenylphosphine molecule completing the metal coordination. The(More)
Non-steroidal antirheumatic agents have the same type of action qualitatively: they are more or less potent inhibitors of prostaglandin synthesis and also influence other mediators of the inflammatory process. Certain risks with these substances are the inevitable side-effects of their antiinflammatory/analgesic action. Experiments to improve this type of(More)