GABA(B) receptors decrease the release of GABA from the striatal terminals within the pars reticulata of the substantia nigra by opposing the increase in the release caused by dopamine D₁ receptors. The dopamine D₁ receptors also increase the release of glutamate from subthalamic terminals in the pars reticulata. Because GABA(B) receptors decrease the… (More)
CaMKIIα is expressed at high density in the nucleus accumbens where it binds to postsynaptic D3 receptors inhibiting their effects. In striatonigral projections, activation of presynaptic D3 receptors potentiates D1 receptor-induced stimulation of cAMP production and GABA release. In this study we examined whether the presynaptic effects of D3 receptor… (More)
d~r dritt~n von dr~i Haup"iehtungen des Verständnisses von "Kultur": a) als eine Summ~ von Wissen, b) als Ensemble von Instilutionen, c) als kollektiv ~ntworfencr, verbindlicher Sinnkosmos. Diesc Unterschei-dunI n.
Located in the remote, impenetrable and incompletely mapped rainforest of the Mosquito Coast, the legendary "Ciudad Blanca" of Honduras was never conquered by the Spanish. With time, it was slowly forgotten. JERS-1 and ERS-2 SAR images are used to identify and to locate the lost city, a task made difficult due to the thick vegetation cover. Among the… (More)
In striatonigral projections activation of dopamine D3 receptors (D3Rs) potentiates the stimulation of GABA release and cAMP production caused by activation of dopamine D1 receptors (D1Rs). Cytoplasmic [Ca(2+)] in the terminals controls this response by modulating CaMKII, an enzyme that depresses D3R action. To examine the effects of dopamine deprivation on… (More)
Ataxia espinocerebelosa tipo 2 (parte A): epidemiología y características clínicas y genéticas Abstract Spinocerebellar ataxia type 2 (SCA2) is an autosomal dominant genetic disease characterized by cerebellar dysfunction associated with slow saccades, early hyporeflexia, severe tremor of postural or action type, peripheral neuropathy, cognitive disorders,… (More)
INTRODUCTION Charcot-Marie-Tooth disease (CMT) is a neuropathy that affects sensory and motor nerves. The most common CMT subtype is CMT1A due to a PMP22 duplication of a 1.5 Mb fragment on the 17p11.2-p12. The development of a specific molecular technique that detects the PMP22 duplication is necessary for the diagnosis of CMT1A. AIM To establish a… (More)
In his Introducción al Ensayo Cronológico para la historia general de la Florida (1722, Ensayo from here on), Andrés Gonzáles de Barcia sounds the alarm against what he terms the dangerous errors, confusions, and inventions by malicious foreign writers who, he laments, fabricate preposterous representations of Florida. The Ensayo accompanied the re-edition… (More)