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The present study estimated genetic parameters for yields of milk, fat, and protein applying REML procedures under test day animal models. The data consisted of 155,494 test day records from 15,756 Friesian cows in first lactation from one region in northern Germany. The models applied included a traditional herd-year-season model for the analysis of single(More)
Genotype by environment interaction can be detected via the estimation of genetic correlations between environments under an animal model based on data comprising genetic links between the strata. Genetic correlations were estimated for protein yield of Holstein cows within and across regions of Germany using REML under an animal model for lactation and(More)
Splay leg is a hereditary syndrome observed in highly varying frequency in newborn piglets. Although the phenotype indicates a muscular weakness, the etiology is still poorly understood. Only recently, the gene expression of muscle atrophy F-box (MAFbx; FBXO32) was proposed as being of diagnostic value for splay leg in piglet. In this study, total RNA from(More)
The congenital splay leg syndrome in piglets is characterized by a temporarily impaired functionality of the hind leg muscles immediately after birth. Etiology and pathogenetic mechanisms for the disease are still not well understood. We compared genome wide gene expression of three hind leg muscles (M. adductores, M. gracilis and M. sartorius) between(More)
In test-day (TD) models, records from individual test days are used to determine lactation production instead of aggregating records. Test-day models have recently gained considerable interest because they are more flexible in handling records from different recording schemes. Compared with only using records of complete lactations, they can reduce the(More)
The melanocortin 4 receptor is expressed in virtually all brain regions of mammals and plays an important role in energy homeostasis. Polymorphisms in this gene may thus be related to growth and obesity. In pigs, a non-synonymous polymorphic site was described (Asp298Asn) and demonstrated to affect cAMP production and to alter adenylyl cyclase signalling.(More)
The myogenic factors (MYF) 5 and 6 are integral to the initiation and development of skeletal muscle and to the maintenance of its phenotype. Thus, they are candidate genes for growth- and meat quality-related traits. We performed a comparative sequence analysis of the MYF5/MYF6 locus in swine, cattle, dog, chicken and zebrafish on the basis of structural(More)
In survival analysis, type traits can be included as covariates to evaluate their use as predictors for survival. One problem in such an analysis is the availability of suitable data. Whereas data on the length of productive life (LPL) of individual cows can be retrieved from milk recording data, for type traits, all cows in the population must be scored(More)
Effectiveness of cluster analysis in detecting application of bST was examined. Field data were manipulated by adding a specified percentage of the true performance to original test day records to simulate application of bST. The partly manipulated data then were analyzed using cluster analysis. Test day milk production data came from 42,779 cows of the(More)
Genetic interference means that the occurrence of one crossover affects the occurrence and/or location of other crossovers in its neighborhood. Of the three components of genetic interference, two are well modeled: the distribution of the number and the locations of chiasmata. For the third component, chromatid interference, there exists only one model. Its(More)