Hermann Koerperich

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BACKGROUND Blood flow can be quantified noninvasively by phase-contrast cine MRI (PC-MRI) in adults. Little is known about the feasibility of the method in children with congenital heart disease. METHODS AND RESULTS In 50 children (mean age 6.2 years, range 1.1 to 17.7 years) with an atrial- or ventricular-level shunt, blood flow rate in the great vessels(More)
BACKGROUND Cardiac MRI is important in the treatment of children with congenital heart disease, but sufficient normative data are lacking. For ventricular volumes and mass, we sought to deliver reference centiles and to investigate sex effects. METHODS AND RESULTS We included 114 healthy children and adolescents, uniformly distributed spanning an age(More)
BACKGROUND AND AIM Despite improvements in surgical revascularisation, limitations like anatomical factors or atherosclerosis limit the success of revascularisation in diabetic patients with critical limb ischaemia. Stem cells were shown to improve microcirculation in published studies. The aim of this study was to evaluate safety, feasibility and efficacy(More)
PURPOSE To provide reference data for atrial size and function during childhood and adolescence by cardiac MR (CMR). MATERIALS AND METHODS We prospectively examined 115 healthy children and adolescents (mean age, 12.4 ± 4.1 years; range, 4.4-20.3 years) by CMR using a stack of standard two-dimensional steady-state free-precession slices acquisition(More)
PURPOSE To evaluate phase-contrast magnetic resonance (MR) imaging for sizing of secundum atrial septal defects (ASDs) and inflow MR angiography for detection of associated venous anomalies in pediatric patients with inconclusive transthoracic echocardiographic (TTE) results. MATERIALS AND METHODS Sixty-five children (mean age, 5.4 years +/- 2.7 [SD])(More)
AIMS To assess the accuracy of different hardware and software settings for left ventricular (LV) volume quantification in children using real-time three-dimensional echocardiography (RT3DE). METHODS AND RESULTS The impact of different matrix transducers (IE 33, X3-1 and VIVID 7, V3) and quantification software settings [TOMTEC; contour-finding activity(More)
BACKGROUND Flow quantification in real time by phase-contrast MRI (PC-MRI) may provide unique hemodynamic information in congenital heart disease, but available techniques have important limitations. We sought to validate a novel real-time magnetic resonance flow sequence in children. METHODS AND RESULTS In 14 pediatric patients (mean age 5.2+/-2.0 years)(More)
BACKGROUND Operator-independent isotropic 3D MRI may greatly simplify the assessment of complex morphology in congenital heart disease. We sought to evaluate the reliability of this new approach. METHODS AND RESULTS In 31 adolescent and adult patients (age, 6 to 42 years; median, 16 years) with congenital heart disease, cardiac morphology was determined(More)
BACKGROUND Congenital heart defects such as coarctation or valvular aortic stenosis are followed by changes in left ventricular myocardial deformation mechanics induced by pressure overload. METHODS Echocardiography was performed in 37 patients (aged 0-27 years, 15 female) with coarctation (27) or valvular aortic stenosis (10) before and after(More)
BACKGROUND The impact of gender and age on cardiac function by cardiac magnetic resonance (CMR) in repaired tetralogy of Fallot (TOF) is unknown, which limits the value of currently discussed volumetric thresholds and the accuracy of individual follow-up. METHODS AND RESULTS In a nationwide, prospective, 14-center study, 407 consecutive patients with(More)