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Since 1953 when for the first time author pointed at correlation between clinical-neuroleptic effectiveness and the extrapyramidal system, more than 50,000 investigations with 30 different short-term and long-term neuroleptics have been carried out on approximately 850 schizophrenics whose extrapyramidal fine movements were tested according to author's(More)
In an open study involving 30 schizophrenic patients the neuroleptic threshold dose (measured via Haase's graphopathological test), the maximum dose, and the maintenance dose were determined. The neuroleptic threshold dose was 5.6 mg/day (0.08 mg/kg body weight); the maximum dose was 11 mg/day (0.16 mg/kg body weight); and the maintenance dose was 6 mg/day(More)
In an open study involving 30 schizophrenic patients the neuroleptic threshold dose (measured using Haase's graphopathological test) and the maximum dose were determined. The neuroleptic threshold dose was 18.5 mg/day (SD = 8.84), the maximum dose was 38.2 mg/day (SD = 4.6). With reference to the effectiveness good to very good results were obtained in 15(More)
BACKGROUND Cold atmospheric plasma could constitute an alternative against multi-drug resistant pathogens. Susceptibility of enterococci to cold atmospheric plasma was investigated in vitro. METHODS 39 clinical isolates of enterococci were grouped dependent on the most important resistance patterns and treated on agar using dielectric barrier discharge(More)
Nosocomial surgical site infections (SSI) are still important complications in surgery. The underlying mechanisms are not fully understood. The aim of this study was to elucidate the possible role of skin flora surviving preoperative antisepsis as a possible cause of SSI. We conducted a two-phase prospective clinical trial in patients undergoing clean(More)
  • Freedman, G Entero, +26 authors Fapwca R Gary Sibbald
  • 2009
Practical treatment of pain in patients with chronic wounds: pathogenesis-guided management. Adsorbtion of serum-derived proteins by primary dressings : implications for dressing adhesion to wounds. 21. Vermeulen H. Ubbink DT. Goossens A. et al. Systematic review of dressings and topical agents for surgical wounds healing by secondary intention. A study to(More)
  • H J Haase
  • 1982
Analgetics are not to be substituted by psychotropic drugs without criticism when it has been found that painful physical ailments are of psychic cause. On the contrary, in individual cases it should be investigated whether a depressive psychosis exists which is better treated with anti-depressants, or whether a schizophrenic psychosis exists which should(More)
  • H J Haase
  • 1980
In spite of considerable advances brought by the introduction of neuroleptics into psychiatry, there is scarcely a group of drugs which has become discredited to such an extent through wrong dosage as the neuroleptics. In 1953 the author discovered by means of his handwriting test the dependence of the essentially antipsychotic effect against psychotic(More)
The following statements can be made on the basis of our study. 1. The butyrophenone bromperidol is an absolutely effective drug of the series of very high-potency neuroleptics, with a mean neuroleptic threshold dose of 5.6 mg/day. The mean optimum dose is 6 mg/day, and the mean maximum dose reaches 11 mg/day, i.e. twice the neuroleptic threshold dose. 2.(More)
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