Herman Ott

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The effects of a single dose of scopolamine alone and in combination with ZK 93426 (a beta-carboline antagonist at the GABAA/BZ receptor complex with weak inverse agonist activity) were tested in two studies. In one study (study 1) the emphasis of enquiry was on different stages of information processing measured by a psychometric battery; in the second(More)
Due to former soil surveys and mapping activities signifi cant amount of soil information has accumulated in Hungary. Present soil data requirements are mainly fulfi lled with these available datasets either by their direct usage or aft er certain specifi c and generally fortuitous, thematic and/or spatial inference. Due to the more and more frequently(More)
Here we investigated the applicability of a computer-aided video-tracking as a method for evaluating potential deficits of neural information processing in patients with AIDS and those showing only positive HIV-seroreactivity. Video-tracking was accompanied with a simultaneous recording of EEG. Eight HIV-positive asymptomatic volunteers and eight(More)
In a pharmacopsychological study, memory impairments after single oral doses of benzodiazepines or placebo were investigated in 40 healthy men aged 20-40 years. The study was designed as a double-blind and placebo-controlled trial. Four independent groups of 10 subjects randomly received either 1 mg lormetazepam, 2 mg lormetazepam, 2 mg flunitrazepam, or(More)
The role of preoperative anxiety in perioperative adaptation is viewed in two different ways. Janis suggested that anxiety is a drive that evokes the cognitive work of worrying. Leventhal stresses the importance of coping behavior for adaptation, while anxiety may or may not accompany this coping process. Both theories have empirical support. The aim of(More)
A screening study was carried out in normal elderly volunteers to determine 1. their scores in measures of memory and information processing 2. how the measures correlate with sample characteristics 3. how the measures correlate with each other and with the EEG. We report here on 111 subjects, 56 women and 55 men aged 53-77 years (63.9 +/- 6.8) with average(More)
SUBJECTS AND METHODS 54 healthy volunteers took part in 3 placebo controlled double-blind trials designed partly as crossover, partly as parallel group studies. The long-acting (elimination half-life greater than 24 h) test drugs diazepam (DIA 5; 10 mg) and flurazepam (FLU 30 mg) were compared to the short-acting drugs (elimination half-life less than 12 h)(More)
PURPOSE The recent development of short-acting benzodiazepines without active metabolites calls for a differentiation between the hangover effects of long-acting (LBD) and short-acting (SBD) benzodiazepines, when used as nighttime sedatives. The question now arises as to which electrophysiological and psychometric tests can record these effects with the(More)