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The main purpose of the present study was to test the hypothesis that persons who stutter, when compared to persons who do not stutter, are less able to assemble abstract motor plans for short verbal responses. Subjects were adult males who stutter and age- and sex-matched control speakers, who were tested on naming pictures and words, using a(More)
The main purpose of the present study was to differentiate between people who stutter and control speakers regarding their ability to assemble motor plans and to prepare (and execute) muscle commands. Adult males who stutter, matched for age, gender, and educational level with a group of control speakers, were tested on naming words and symbols. In(More)
The cell-cell adhesion molecule E-cadherin has been shown to suppress invasive growth of epithelial cells in vitro, and loss of its expression is thought to be important in invasion and metastatic potential of epithelial tumors in vivo. We retrospectively studied the level of E-cadherin expression in 50 primary head and neck squamous-cell carcinomas (HNSCC)(More)
AIM To compare the predictive value of sentinel lymph node (SN) mapping between patients with colon and rectal cancer. PATIENTS AND METHODS An ex vivo SN procedure was performed in 100 patients with colon and 32 patients with rectal cancer. If the sentinel node was negative, immunohistochemical analyses using two different antibodies against cytokeratins(More)
This study investigates reaction times in the fluent speech utterances of stutterers and nonstutterers under several experimental conditions. Twenty adult stutterers and twenty matched controls produced utterances of three lengths--one syllable words, polysyllabic words, and sentences--in two conditions of time pressure (high and low) and two conditions of(More)
Electromyograph (EMG) signals of the m. orbicularis oris inferior evoked by lip-rounding gestures were analyzed to see whether stutterers in their perceptually fluent speech had higher levels of EMG and longer EMG durations. The relationship between levels of EMG and durations of elevated muscle activity was investigated, and a search for the best(More)
Four experienced speakers were trained to produce isolated vowels with different degrees of abruptness of voice onset while keeping the maximum sound level and the duration of the sounds constant. A total of 420 vowel tokens were rated for abruptness of voice onset by 11 trained speech scientists in order to study the reliability of the ratings, which was(More)
The immunohistochemical expression patterns of cytokeratins 8 and 18 and vimentin were examined in frozen sections of 120 human mucosal squamous cell carcinomas with special emphasis on the topological distribution in the tumour. This was done in order to evaluate in squamous cell carcinoma a particular expression pattern observed recently by us in(More)
OBJECTIVE To investigate the effects of infant orthopedics (IO) on the language skills of children with complete unilateral cleft lip and palate (UCLP). DESIGN In a prospective randomized clinical trial (Dutchcleft), two groups of children with complete UCLP were followed up longitudinally: one group was treated with IO based on a modified Zurich approach(More)