Herbert W Maisenbacher

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Bone sialoprotein (BSP) is a noncoflagenous bone matrix protein that is important for both mineralization and cell-cell interactions. Tissue studies in primary breast cancers have shown that immunohistochemical expression of BSP is associated with a high incidence of bone metastases in the course of the disease. We used a RIA to investigate the importance(More)
Double-outlet right atrium (DORA) is a type of atrioventricular septal defect that is described as an extreme leftward deviation of the lower portion of the interatrial septum, resulting in insertion into the atrial wall left and posterior to the mitral orifice. This rare anomaly, which has been reported in humans and only just recently in cats, was(More)
OBJECTIVE To determine if topically administered ophthalmic atropine affects heart rate or rhythm in clinically normal dogs. METHODS Two groups of 15 healthy dogs were evaluated, one consisting of dogs weighing <15 kg, the other consisting of dogs weighing >15 kg. Each dog was suited with a Holter monitor. At start time 0, dogs received one drop of(More)
Calculation of stenotic valve area can aide in the determination of the severity of the lesion. While use of Doppler derived pressure gradients are widely used and easily interpreted, certain situations may make these measurements less reliable. The purpose of this paper is to demonstrate the technique for measuring the stenotic valve area and illustrate(More)
An 11-year-old female spayed Labrador Retriever was presented for a draining, painful subcutaneous mass palpated over a previously implanted pacemaker generator. Infection was suspected and the mass was removed surgically. On cut surface, the mass was friable and mottled tan to brown with firm pale tan nodules, surrounding the pacemaker lead wire adjacent(More)
OBJECTIVE To evaluate the cardiopulmonary effects of low-pressure (6 mmHg) peritoneal insufflation of varying duration in healthy cats during ovariectomy (OVE). STUDY DESIGN Prospective, randomized study. ANIMALS Female cats (n = 24). METHODS After anesthesia induction, cats had short (Short LAP; n = 8) or long duration (Long LAP; n = 8) laparoscopic(More)
We characterized the pharmacokinetics and dynamics of dichloroacetate (DCA), an investigational drug for mitochondrial diseases, pulmonary arterial hypertension, and cancer. Adult Beagle dogs were orally administered 6.25 mg/kg q12h DCA for 4 weeks. Plasma kinetics was determined after 1, 14, and 28 days. The activity and expression of glutathione(More)
Computed tomographic angiography (CTA) is a useful diagnostic modality that is becoming more widely available in veterinary medicine. Its three-dimensional imaging capabilities allow a template for planning surgical procedures, accurate lesion measurements, and it is considerably less expensive than other comparable modalities. Selective CTA is described(More)