Herbert W.M. Plokker

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OBJECTIVE To determine if embolization of pulmonary arteriovenous malformations (PAVMs) decreases the occurrence of migraine. METHODS All 105 patients with hereditary hemorrhagic telangiectasia (HHT), minimum age 16 years, who underwent an embolization of PAVM in our hospital between June 1995 and April 2004, were included in this study. A structured(More)
Plasma concentrations of the third complement component (C3) predict the risk of myocardial infarction. Because chylomicrons stimulate C3 production by adipocytes in vitro, we investigated plasma C3 changes in vivo after an oral fat load. Thirty-seven subjects (20 normolipidemic patients with coronary artery disease [CAD] and 17 healthy control subjects)(More)
Migraine is a common neurological disorder with a great impact on the quality of life and social activities. Pulmonary arteriovenous malformations (PAVMs) are mostly congenital, with a prevalence of 5-50% in patients with hereditary hemorrhagic telangiectasia (HHT). A high prevalence of PAVMs is found in patients with HHT and migraine. Embolization of PAVMs(More)
echocardiographic signs of pulmonary hypertension at the initial presentation [6]. Interestingly, the development of CTEPH is not associated with common risk factors for venous thromboembolism, such as factor V Leiden, factor II mutation, deficiency of antithrombin, protein C and protein S or a prothrombin G20210A gene mutation [7]. The prevalence of these(More)
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