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In this paper, we propose the use of multiscale amplitude-modulation-frequency-modulation (AM-FM) methods for discriminating between normal and pathological retinal images. The method presented in this paper is tested using standard images from the early treatment diabetic retinopathy study. We use 120 regions of 40 x 40 pixels containing four types of(More)
The human scalp-recorded vertex-positive brain stem response to a click or high-frequency tone pip is an excellent audiometric indicator. Its latency of 6-9 ms is practically independent of the polarity of the stimulus but is inversely related to intensity. With a 4,800- or 2,400-Hz tone pip (filtered click) its threshold of detectability is usually at or(More)
Plasmacortisol levels were examined to assess the stress of dogs in a county animal shelter. Groups of dogs confined in the shelter for their 1st, 2nd, or 3rd day had higher cortisol levels than did a group maintained in the shelter for more than 9 days. Dogs in the shelter for an intermediate period (Day 4-9) had intermediate levels of cortisol. The(More)
Proper choices of stimuli and of brain stem electric responses allow us to estimate peripheral auditory thresholds at 500, 1 000, 2 000 and 4 000 Hz with an accuracy of about +/- 10 dB. With the help of sedation (secobarbital), such audiograms may be obtained from each ear of a child of any age in a single session. Tone pips (filtered clicks) or very brief(More)
Human and animal studies indicate that stress during pregnancy can exert long-term effects on the development of the offspring, effects that appear to be mediated in part by the hypothalamic-pituitary-adrenal (HPA) axis. In this experiment changes in levels of a variety of HPA and other hormones in both pregnant rats and their fetuses were investigated.(More)
Pregnant rats injected with 20 micrograms of corticotropin-releasing factor (CRF) from day 14 through 21 gained less weight during gestation than did saline-injected controls. The offspring of CRF-injected females differed from the offspring of control females in several ways: males and females weighed less during the first 2 weeks of life, males had(More)
Auditory evoked potentials are nearly all on-effects and the 'effective stimuli' for them are necessarily brief. Their frequency specificity is therefore limited, especially for the brainstem responses, because of the well-known trade-off between duration and frequency specificity. Brainstem responses are of special interest because they are unchanged in(More)