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  • Katsutoshi Ozaki, Rosanne Spolski, +10 authors Warren J Leonard
  • Medicine, Biology
  • The Journal of Immunology
  • 2004 (First Publication: 1 November 2004)
  • IL-21 is a type I cytokine whose receptor is expressed on T, B, and NK cells. Within the B cell lineage, IL-21 regulates IgG1 production and cooperates with IL-4 for the production of multiple AbContinue Reading
  • Dmitri Loukinov, Elena M Pugacheva, +21 authors Victor V Lobanenkov
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences…
  • 2002 (First Publication: 14 May 2002)
  • CTCF, a conserved, ubiquitous, and highly versatile 11-zinc-finger factor involved in various aspects of gene regulation, forms methylation-sensitive insulators that regulate X chromosomeContinue Reading
  • Giovanna Schiavoni, Fabrizio Mattei, +5 authors Lucia Gabriele
  • Medicine, Biology
  • The Journal of experimental medicine
  • 2002 (First Publication: 2 December 2002)
  • Interferon (IFN) consensus sequence-binding protein (ICSBP) is a transcription factor playing a critical role in the regulation of lineage commitment, especially in myeloid cell differentiation. InContinue Reading
  • Elena M Klenova, Herbert C. Morse, Rolf Ohlsson, Victor V Lobanenkov
  • Biology, Medicine
  • Seminars in cancer biology
  • 2002 (First Publication: 1 October 2002)
  • CTCF is a ubiquitous 11 zinc finger (ZF) protein with highly versatile functions: in addition to transcriptional silencing or activating in a context-dependent fashion, it organizes epigeneticallyContinue Reading
  • Alexander L. Kovalchuk, Chen-Feng Qi, +10 authors Herbert C. Morse
  • Medicine, Biology
  • The Journal of experimental medicine
  • 2000 (First Publication: 16 October 2000)
  • Chromosomal translocations juxtaposing the MYC protooncogene with regulatory sequences of immunoglobulin (Ig) H chain or kappa (Igκ) or lambda (Igλ) L chain genes and effecting deregulated expressionContinue Reading