Herbert C. Francis

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The aims of the study were to provide valid comparative data for personal exposures to dust and endotoxins for different occupations and to calculate comparative data for the contamination of organic dusts with endotoxin. Nine different occupational settings were studied, drawn from the textile, agricultural and animal handling industries. Samples were(More)
BACKGROUND House dust mite allergens play an important role in inducing IgE-mediated sensitization and the development of bronchial hyperresponsiveness (BHR) and asthma. This study investigated the relationship between mite allergen exposure and the clinical activity and severity of asthma. METHODS Nonsmoking adult patients with asthma (n = 53) were(More)
BACKGROUND Evidence from laboratory studies suggests that air pollution can produce bronchoconstriction and respiratory symptoms in selected subjects, but the relevance of these findings to exposure to natural pollution is unclear. This study was performed to determine whether air pollution at typical levels found in the UK has demonstrable effects on(More)
  • A Vyas, C A Pickering, +4 authors R M Niven
  • 2000
OBJECTIVES To find the nature and incidence of symptoms experienced by a large sample of hospital endoscopy nurses. To find whether nurses in endoscopy units develop asthma under current working conditions in endoscopy units. To obtain analytically reliable data on exposure concentrations of glutaraldehyde (GA) vapour in endoscopy units, and to relate them(More)
Laboratory-based studies have shown that ozone and nitrogen dioxide can potentiate the effect of allergen in sensitized asthmatic subjects, but it is not known whether this interaction is important under natural exposure conditions. Thirty-five subjects with clinical diagnoses of asthma or chronic obstructive pulmonary disease and with a provocative dose(More)
Many types of precipitin test for tuberculosis based on the use of tuberculin and various extracts have been developed by previous investigators. In general these tests have been unsatisfactory because of their lack of specificity. In 1929 Doan' reported a precipitin test for tuberculosis in which the phosphatide fraction isolated from the tubercle bacillus(More)
Jean DuMortier from whom he received a rich physical and mental' inheritance. His early education was received in the Norwalk public schools and at Harstrom's Preparatory School. He went to Williams College for two years, where he creditably participated in athletics-swimming, track, and football. His last two years of college were spent at Columbia(More)
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