Herbert Büchels

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BACKGROUND The sentinel lymph nodes (SLNs) as the primary targets for lymphatic metastases can be removed selectively by gamma probe-guided sentinel lymph nodectomy (SLNE) in nearly all patients with cutaneous melanoma. Correspondingly high standards in terms of specificity, sensitivity, and microstaging are required for the evaluation of SLNs. METHODS(More)
BACKGROUND Each melanoma is drained by one or, occasionally, several individual lymph nodes within the nearest lymph node region (sentinel lymph node). OBJECTIVE By histopathologic examination of the removed sentinel lymph node (SLN), it is possible to select patients clinically according to stage I or II (UICC classification), but who, microscopically,(More)
BACKGROUND Primary cutaneous large B-cell lymphoma of the leg (LBCLL) is a recently defined type of non-Hodgkin's lymphoma. It forms a separate category in the new classification of primary cutaneous lymphomas elaborated by the European Organization for Research and Treatment of Cancer. It is associated with a less favorable prognosis than the most(More)
Die Sentinel-Lymphknotenbiopsie (Sentinel-Node-Biopsie, SNB) ist ein diagnostisches Verfahren beim Mammakarzinom, mit dem der Nodalstatus durch selektive Entnahme und Untersuchung des (der) Lymphknoten mit der höchsten Wahrscheinlichkeit für eine Metastasierung bestimmt wird. Hauptziel der Methode ist eine vollständige Erfassung der Patientinnen mit(More)
The sentinel lymph node dissection (SLND) is one of the most striking developments in the treatment of melanoma. Since the first report by Morton et al. in 1992, the method has been refined, and its use has increased. Introduced as an alternative to elective lymph node dissection (ELND), it has rapidly made its way into clinical practice. SLND allows(More)
In cutaneous melanoma, biopsy of the first tumor-draining lymph node (Sentinel node, SLN) may replace routine elective lymph-node dissection (ELND). The SLN has been shown to contain the first micrometastasis in early lymphatic tumor dissemination. As micrometastases were identified in 10–30 % of stage I (AJCC/UICC) patients, sentinel lymphonodectomy (SLND)(More)
The objective of our trial was to evaluate the significance and usefulness of sentinel lymphadenectomy (SLNE) for the staging of regional lymph nodes in breast cancer patients. The study presented illustrates the method and our results. As has been documentated for melanoma, the first lymph node [sentinel node (SLN)] to receive lymphatic drainage from a(More)
Arteriovenous fistulas of the vertebral artery are in most cases caused by penetrating injuries. This report concerns a patient with ankylosing spondylitis, whose fistula most probably was brought about by puncture of the internal jugular vein for aorto-coronary-bypass surgery.
For decades the results of elective lymph node dissection (ELND) are differently discussed, so that it is not definitely recommended at present the less so since the morbidity of this operation can't be neglected. Since the beginning of 1995 we practice a gamma-probe guided sentinel lymphonodectomy (SLNE) on patients with melanoma from a Breslow tumor(More)