Heracles D Dellagrammaticas

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We studied the pharmacokinetics and efficacy of cefotaxime in 32 neonates with severe gram-negative infections. Many of these patients had been treated unsuccessfully with combinations of antibiotics. Eighty-one percent of these patients were cured, 6% improved, and 13% had treatment failures; there were three deaths. Eighteen patients received cefotaxime(More)
Samples from the pharynx, stomach, duodenum or jejunum, and faeces were collected on 7 days between 1st and 28th day from neonates weighing less than 1.5 kg at birth who were fed by transpyloric tube. These were cultured on selective and non-selective media, and the results were expressed in a semi-quantitative manner. The number of bacterial species and(More)
AIM To assess the role of etamsylate in reducing the risk of haemorrhagic brain damage and its consequences. DESIGN Follow up of babies recruited into a randomised controlled trial. METHODS A total of 334 infants born before 33 weeks gestation in France and Greece were randomly allocated within the first four hours of birth either to receive etamsylate(More)
In babies of very low birth weight (less than 1500 g) we studied the effect of head up tilting on oxygenation, respiratory rate, heart rate and blood pressure (n = 23), on gastric emptying (n = 10), and on weight gain (n = 6). Head up tilting to 45 degrees achieved the best oxygenation at the angles studied, and decreased the respiratory and heart rates;(More)
Brain abscess is a rare complication of staphylococcal bacteremia in infants. Here we present a case of a premature infant who developed multiple brain abscesses 12 weeks following an episode of inadequately treated Staphylococcus aureus sepsis. The abscess developed in the absence of trauma, prior surgery, cyanotic heart disease, or immune defect. The(More)
The aim of this retrospective study was to evaluate the clinical efficacy in terms of mortality and long-term morbidity of third generation cephalosporins and amikacin in combination for the treatment of gram-negative bacterial meningitis in a homogeneous group of neonates. A 15-year experience (1983-1997) with 72 term neonates without central nervous(More)
An outbreak of enterovirus infection occurred among neonates in a maternity hospital between July 7 and 22, 1999. Twenty neonates became ill (18 confirmed and two probable), an attack rate of 33%. The incubation period ranged from three to six days (mean, 4.2). The male:female ratio was 11:9 and the mean age at the onset of illness was 5.5 days. All the(More)
A newborn male with cri-du-chat syndrome, congenital nuclear cataracts, microspherophakia, and probably ectopic lenses is reported. Microspherophakia in cri-du-chat syndrome has not been previously described. The congenital cataracts were inherited from his mother who had a balanced 5;13 translocation; the two events are considered to be coincidental and a(More)
Radiological investigations have become accepted as an important part of the range of facilities required to support severely ill newborn babies. Increasing numbers of these very small premature babies now survive although they may undergo a considerable number of diagnostic X-ray examinations within the first few weeks of life. Since the infants are so(More)