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It has long been recognized that it can be tedious and even infeasible for system administrators to figure out critical security problems residing in full attack graphs, even for small-sized enterprise networks. Therefore a trade-off between analysis accuracy and efficiency needs to be made to achieve a reasonable balance between completeness of the attack(More)
In recent years, as mobile smart device sales grow quickly, the development of mobile applications (apps) keeps accelerating, so does mobile app repackaging. Attackers can easily repackage an app under their own names or embed advertisements to earn pecuniary profits. They can also modify a popular app by inserting malicious payloads into the original app(More)
Alzheimer's disease (AD) is characterized by the dysfunction or loss of a vulnerable group of neurons. At present, only a few options exist for treating neurodegenerative diseases effectively. Advances in stem cell research have raised the hope and possibility for therapy in neurodegenerative diseases. In AD transgenic animal models, stem cell(More)
Because it is not hard to reverse engineer the Dalvik bytecode used in the Dalvik virtual machine, Android application repackaging has become a serious problem. With repackaging, a plagiarist can simply steal others' code violating the intellectual property of the developers. More seriously, after repack-aging, popular apps can become the carriers of(More)
Both RhoA/ROCK and NF-κB signaling pathways play important roles in the pathogenesis of diabetic nephropathy (DN). However, it remains unknown whether and how RhoA/ROCK regulates NF-κB signaling in diabetic kidneys. In cultured glomerular mesangial cells (GMCs), the high glucose-activated NF-κB nuclear translocation and DNA binding activity were attenuated(More)
BACKGROUND Our previous studies demonstrated that berberine could improve the renal function in rats and mice with diabetic nephropathy (DN) and inhibit extracellular matrix (ECM) component, fibronectin (FN) expression in rat mesangial cells (MCs) cultured under high glucose. However, the molecular mechanisms have not been fully elucidated. OBJECTIVE To(More)
An app market's vetting process is expected to be scal-able and effective. However, today's vetting mechanisms are slow and less capable of catching new threats. In our research, we found that a more powerful solution can be found by exploiting the way Android malware is constructed and disseminated, which is typically through repackaging legitimate apps(More)
Malignant gliomas represent one of the most aggressive types of cancers and their recurrence is closely linked to acquired therapeutic resistance. A combination of chemotherapy is considered a promising therapeutic model in overcoming therapeutic resistance and enhancing treatment efficacy. Herein, we show by colony formation, Hochest 33342 and TUNEL(More)
Curcumin, a major polyphenol from the golden spice Curcuma longa commonly known as turmeric, has been recently discovered to have renoprotective effects on diabetic nephropathy (DN). However, the mechanisms underlying these effects remain unclear. We previously demonstrated that the sphingosine kinase 1-sphingosine 1-phosphate (SphK1-S1P) signaling pathway(More)
The accumulation of glomerular extracellular matrix proteins, especially fibronectin (FN), is a critical pathological characteristic of diabetic renal fibrosis. Inflammation mediated by nuclear factor-κB (NF-κB) plays a critical role in the pathogenesis of diabetic nephropathy (DN). RhoA/ROCK signaling is responsible for FN accumulation and NF-κB(More)