Heping Li

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Esophageal squamous cell carcinoma (ESCC) is the major histological type of esophageal cancer in developing countries. The prognosis and survival rate of ESCC are very poor. Recently, microRNAs (miRNAs) have emerged as important regulators of cancer cell biological processes. To better understanding the molecular mechanisms by which they regulate the(More)
A novel method based on space-time image features is proposed for automatic behavior modeling and recognition. The method is composed of the following three steps: (1). Video sequences are converted into a space-time image, and the image is divided into equal length segments; (2). From these segments, an unsupervised technique based on Dynamic Time Warping(More)
BACKGROUND Several studies have found that DDR2 is up-regulated in many tumor types and facilitates tumor progression. However, the role of DDR2 in hepatocellular carcinoma (HCC) progression and its downstream signaling pathways remain unclear. METHODS DDR2 expression was assessed in several cell lines and 112 pairs of HCC and matched adjacent(More)
It has always been very difficult to recognize realistic actions from unconstrained videos because there are tremendous variations from camera motion, background clutter, object appearance and so on. In this paper, a Single-Feature Hierarchical Latent Dirichlet Allocation model called SF-HLDA by extending Latent Dirichlet Allocation to the hierarchical one(More)
—In this paper, a novel Chinese character localization method is proposed for texts in advertising images. To deal with the texts with gradient color, a color clustering method based on edge is introduced to separate the color image into homogeneous color layers. To solve the problem of locating characters varied in size, style and arranged in irregular(More)
Transcriptional co-activator Yes-associated protein (YAP) and transcriptional co-activator with PDZ-binding motif (TAZ) are key oncogenes in mammalian cells. Activities of YAP and TAZ are largely restricted by the Hippo tumor suppressor pathway through phosphorylation-ubiquitination mechanisms. The involvement of microRNA in cancer progression has recently(More)
Increasing demand for natural rubber prompts studies into the mechanisms governing the productivity of rubber tree (Heveabrasiliensis). It is very interesting to notice that a rubber tree of clone PR107 in Yunnan, China is reported to yield more than 20 times higher than the average rubber tree. This super-high-yielding (SHY) rubber tree (designated as(More)
In this paper, we aimed to improve the carbohydrate productivity of Spirulina platensis by generating mutants with increased carbohydrate content and growth rate. ARTP was used as a new mutagenesis tool to generate a mutant library of S. platensis with diverse phenotypes. Protocol for rapid mutation of S. platensis by 60 s treatment with helium driven ARTP(More)
—The italic detection and slant rectification is a key step of optical character recognition (OCR). In this paper, a novel method is proposed to detect and rectify italic characters in Chinese advertising images. Based on observations on structures of many characters, the centroid angle is proposed and a statistical study on it is presented. According to(More)