Henryk Radwan

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STUDY OBJECTIVES To evaluate the effect of body position on REM-related obstructive sleep apnea (OSA) patients. DESIGN Retrospective analysis. PATIENTS 100 consecutive adult OSA patients (apnea-hypopnea index [AHI] > or = 5) who had > or = 10 min of REM sleep in both supine and lateral postures. REM-related OSA was defined by previously used criteria(More)
Serine proteinases of 42, 22 and 14 kDa were purified from the culture fluid of Streptomyces olivaceoviridis by FPLC. The first 14 amino acids at their N-termini were identical and coincide with the N-terminal amino acid sequence of 92-kDa chitinase, which was found to hydrolyse casein. The four proteins hydrolyse synthetic substrates at the carboxyl group(More)
OBJECTIVES/HYPOTHESIS To compare demographic and polysomnographic data of sleepy versus nonsleepy severe obstructive sleep apnea (OSA) patients according to the Epworth Sleepiness Scale (ESS). STUDY DESIGN Retrospective cohort. METHODS Six hundred forty-four consecutive severe (apnea-hypopnea index [AHI] >or= 30) adult OSA patients who underwent a(More)
The hypothesis was tested that unilateral dopamine deficiency leading to the contralateral extrapyramidal syndrome (hemi-parkinsonism) would cause distinctly asymmetric EEG sleep patterns. In 7 hemi-Parkinson's patients 2 nights of sleep were monitored along with pre-sleep waking periods. No medication was given prior to the first night. The second night(More)
Rapid Eye Movement (REM) sleep behavior disorder is characterized by the intermittent loss of REM-related muscle atonia and the appearance of elaborated motor behaviors (sometimes violent behavior) and vocalizations associated with dream mentation. Nine patients were diagnosed in our Sleep Disorders Unit with this syndrome during the period August(More)
The aim of this study was to evaluate demographic and polysomnographic characteristics of positional (PPJ) and non-positional obstructive (NPP) sleep apnea (OSA) patients in 2077 OSA patients diagnosed in our Sleep Disorders Unit during a period of 10 years. An OSA patient is defined as positional if he has twice as many or more breathing abnormalities(More)
BACKGROUND Cheyne-Stokes Respiration (CSR) is a common finding in Chronic Heart Failure and Stroke patients. The body position effect during sleep on obstructive breathing abnormalities is well known. However, the effect of body position during sleep on breathing abnormalities of central type like CSR has not been well documented. MATERIAL/METHODS Six(More)