Learn More
BACKGROUND Retinal ischemia induces intraocular neovascularization, which often leads to glaucoma, vitreous hemorrhage, and retinal detachment, presumably by stimulating the release of angiogenic molecules. Vascular endothelial growth factor (VEGF) is an endothelial-cell-specific angiogenic factor whose production is increased by hypoxia. METHODS We(More)
The transforming growth factor-beta s are peptide growth factors known to play a central role in wound healing. Using a specific, in vitro assay of cell growth inhibition, we have detected transforming growth factor-beta (TGF-beta) in 24/24 aqueous humor specimens from eyes undergoing cataract extraction with intraocular lens implantation. The amount of(More)
OBJECTIVE To review the published literature and summarize clinically relevant information about novel, or emerging, surgical techniques for the treatment of open-angle glaucoma and to describe the devices and procedures in proper context of the appropriate patient population, theoretic effects, advantages, and disadvantages. DESIGN Devices and procedures(More)
PURPOSE To describe the incidence of, and risk factors for, surgical complications reported during and within the first post-operative month after trabeculectomy in the Collaborative Initial Glaucoma Treatment Study (CIGTS). DESIGN Review of prospectively collected data from a multicenter, randomized clinical trial. METHODS Complications were tabulated(More)
PURPOSE To determine the change in intraocular pressure (IOP) after cataract extraction in the observation group of the Ocular Hypertension Treatment Study. DESIGN Comparative case series. PARTICIPANTS Forty-two participants (63 eyes) who underwent cataract surgery in at least 1 eye during the study and a control group of 743 participants (743 eyes) who(More)
BACKGROUND Glaucoma is an acquired degeneration of the optic nerve and a leading cause of blindness worldwide. Medical and surgical treatments that decrease intraocular pressure may prevent visual impairment and blindness. PURPOSE To compare the effectiveness of medical, laser, and surgical treatments in adults with open-angle glaucoma with regard to(More)
PURPOSE To determine the importance that US glaucoma specialists place on attributes of eye drops for lowering intraocular pressure. MATERIALS AND METHODS We performed a cross-sectional survey by conducting a telephone interview with 113 members of the American Glaucoma Society. We administered a willingness-to-pay (WTP) instrument asking glaucoma(More)
  • H D Jampel
  • 2001
PURPOSE To determine how glaucoma patients with various degrees of vision loss rate their vision, and to determine if the Esterman binocular visual field test and other visual function tests correlate with those ratings. METHODS Two hundred thirty-seven glaucoma patients evaluated their vision using 2 utility tests, the linear rating scale and the time(More)
PURPOSE To measure choroidal thickness and to determine parameters associated with it. DESIGN Cross-sectional study. PARTICIPANTS Seventy-four glaucoma patients and glaucoma suspects. METHODS Spectral domain optical coherence tomography (SD-OCT) scans were obtained to estimate average choroidal thickness in a group of glaucoma suspects and glaucoma(More)