Henry Jampel

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PURPOSE To determine the distribution of transforming growth factor type beta (TGF-beta) in the anterior segment of the human eye. This knowledge is important because TGF-beta may regulate various physiologic responses in the anterior segment by controlling cell proliferation and differentiation, angiogenesis, and extracellular matrix composition. METHODS(More)
OBJECTIVE The posterior pole ganglion cell bodies form a substantial fraction of the retinal thickness, prompting the authors to study the feasibility of detecting, by scanning retinal thickness analysis, retinal changes at the posterior pole due to glaucomatous damage. STUDY DESIGN Nonconsecutive case series. PARTICIPANTS One or both eyes of patients(More)
We designed and evaluated a new test for the detection of early glaucoma damage in 133 persons who were classified as normal, suspected of having glaucoma, or having glaucoma. The test stimulates the entire visual field with a flashing white light under dark-adapted conditions. It can be performed easily by a high proportion of subjects and is as(More)
OBJECTIVE To determine if, and at what point, glaucoma affects spoken reading speed. METHODS Data were collected from the Salisbury Eye Evaluation, a population-based evaluation of visual function and disability in the elderly population. Nonscrolling text was displayed on a screen and the rate words were read aloud was measured. Subjects reading slower(More)
PURPOSE To assess patient adherence and behaviors with topical once-daily therapy for glaucoma. DESIGN Prospective, observational cohort study. PARTICIPANTS One hundred ninety-six patients with glaucoma who were being treated with a prostaglandin analog in 1 or both eyes at the Scheie or Wilmer Eye Institutes between August 2006 and June 2007. METHODS(More)
PURPOSE To determine which measures of the binocular visual field correlate best with the patient's assessment of vision. METHODS Esterman binocular visual field testing and four other binocular visual field tests (designated peripheral 20 dB [p20], peripheral 22 dB [p22], central 24 dB [c24] and central 26 dB [c26]) were performed in 101 patients with(More)
We have examined the possibility that hyperthermia, such as that occurring during fever, may benefit the immune response. The effect of temperature on the in vitro immune response of unprimed murine spleen cells against the antigen sheep erythrocytes was tested. Hyperthermia potently augmented the plaque-forming cell response. Temperature-sensitive events(More)
Purpose: To identify risk factors for poor adherence to topical once daily therapy for glaucoma. Design: Prospective, observational cohort study. Participants: A total of 196 patients with glaucoma who were being treated with a prostaglandin analog in 1 or more eyes at the Scheie or Wilmer Eye Institutes between August 2006 and June 2007. Methods:(More)
PURPOSE To investigate the impact of an intervention program to improve adherence with topical, once daily therapy for glaucoma. DESIGN Randomized controlled clinical trial. PARTICIPANTS Sixty-six patients with glaucoma being treated with a prostaglandin analog in 1 or both eyes at the Scheie Eye Institute or Wilmer Eye Institute between November 2006(More)
We evaluated the reliability of optic disk area and disk rim area measurements obtained with the Humphrey Retinal Analyzer from ten repeat fundus images each of one eye of ten normal subjects and ten subjects with increased intraocular pressure. Variability of rim and disk areas was not significantly different between these two groups (P greater than .05),(More)