Henry Haining Zhang

Learn More
Web caching and prefetching are well known strategies for improving the performance of Internet systems. When combined with web log mining, these strategies can decide to cache and prefetch web documents with higher accuracy. In this paper, we present an application of web log mining to obtain web-document access patterns and use these patterns to extend(More)
Caching is one of the most e ective techniques for improving the performance of Internet systems. The heart of a caching system is its page replacement policy, which decides which page to replace in a cache by a new one. Di erent caching policies have dramatically di erent e ects on the system performance. In this paper, we extend the well-known GDSF(More)
Caching is a well-known strategy for improving the performance of Web-based systems. The heart of a caching system is its page replacement policy, which selects the pages to be replaced in a cache when a request arrives. In this paper, we present a Web-log mining method for caching Web objects and use this algorithm to enhance the performance of Web caching(More)
Web caching and prefetching have been studied in the past separately. In this paper, we present an integrated architecture for Web object caching and prefetching. Our goal is to design a prefetching system that can work with an existing Web caching system in a seamless manner. In this integrated architecture, a certain amount of caching space is reserved(More)
Supercoiled plasmid DNA is susceptible to fluid stress in large-scale manufacturing processes. A capillary device was used to generate controlled shear conditions and the effects of different stresses on plasmid DNA structure were investigated. Computational fluid dynamics (CFD) analysis was employed to characterize the flow environment in the capillary(More)
Caching and prefetching are well known strategies for improving the performance of Internet systems. The heart of a caching system is its page replacement policy, which selects the pages to be replaced in a proxy cache when a request arrives. By the same token, the essence of a prefetching algorithm lies in its ability to accurately predict future request.(More)
Case-based reasoning aims to use past experience to solve new problems. A strong requirement for its application is that extensive experience base exists that provides statistically significant justification for new applications. Such extensive experience base has been rare, limiting most CBR applications to be confined to small-scale problems involving(More)
Heterogeneity of C-terminal lysine levels often observed in therapeutic monoclonal antibodies is believed to result from the proteolysis by endogenous carboxypeptidase(s) during cell culture production. Identifying the responsible carboxypeptidase(s) for C-terminal lysine cleavage in CHO cells would provide valuable insights for antibody production cell(More)
  • 1