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BACKGROUND The HER2 gene, which encodes the growth factor receptor HER2, is amplified and HER2 is overexpressed in 25 to 30 percent of breast cancers, increasing the aggressiveness of the tumor. METHODS We evaluated the efficacy and safety of trastuzumab, a recombinant monoclonal antibody against HER2, in women with metastatic breast cancer that(More)
This paper describes a new algorithm for solving the hidden surface (or line) problem, to more rapidly generate realistic images of 3-D scenes composed of polygons, and presents the development of theoretical foundations in the area as well as additional related algorithms. As in many applications the environment to be displayed consists of polygons many of(More)
We introduce ideas, proposed technologies, and initial results for an office of the future that is based on a unified application of computer vision and computer graphics in a system that combines and builds upon the notions of the CAVETM, tiled display systems, and image-based modeling . The basic idea is to use real-time computer vision techniques to(More)
In many scientific and technical endeavors, a three-dimensional solid must be reconstructed from serial sections, either to aid in the comprehension of the object's structure or to facilitate its automatic manipulation and analysis. This paper presents a general solution to the problem of constructing a surface over a set of cross-sectional contours. This(More)
Conventional projector-based display systems are typically designed around precise and regular configurations of projectors and display surfaces. While this results in rendering simplicity and speed, it also means painstaking construction and ongoing maintenance. In previously published work, we introduced a vision of projector-based displays constructed(More)
We describe initial results which show “live” ultrasound echography data visualized within a pregnant human subject. The visualization is achieved by using a small video camera mounted in front of a conventional head-mounted display worn by an observer. The camera’s video images are composited with computer-generated ones that contain one or more 2D(More)
This paper introduces a proof-of-concept telepresence system that offers fully dynamic, real-time 3D scene capture and continuousviewpoint, head-tracked stereo 3D display without requiring the user to wear any tracking or viewing apparatus. We present a complete software and hardware framework for implementing the system, which is based on an array of(More)
BACKGROUND Respiratory disease in patients with cystic fibrosis is characterized by airway obstruction caused by the accumulation of thick, purulent secretions, which results in recurrent, symptomatic exacerbations. The viscoelasticity of the secretions can be reduced in vitro by recombinant human deoxyribonuclease I (rhDNase), a bioengineered copy of the(More)
BACKGROUND AND PURPOSE To determine the frequency of mucositis and associated outcomes in patients receiving radiotherapy (RT) for head and neck cancer through a systematic review of recently published literature. MATERIALS AND METHODS According to the study protocol, databases were searched for randomized clinical trials (English only, 1996-1999) of(More)