Henry F. Sears

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The binding of monoclonal antibody specific for colon carcinoma was inhibited by serum from patients with adenocarcinoma of the colon but not by serum from patients with other bowel diseases or from healthy volunteers. Of other malignancies studied, serum from two patients with gastric carcinoma and two patients with pancreatic carcinoma also inhibited the(More)
A phase-I clinical trial of a murine monoclonal antibody that specifically suppresses growth of human gastrointestinal tumours in athymic mice was conducted in four patients, who were given 15-200 mg purified antibody. The monoclonal antibody persisted in the circulation for more than a week when more than 15 mg was given. Antibodies against mouse(More)
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The human c-myc proto-oncogene is the genomic homologue of the transforming sequences found in MC29, an avian retrovirus that can cause myelocytomatosis, carcinoma, sarcoma and lymphoma (Graf & Beug, 1978; Enrietto et al., 1983). Alterations in the structure or expression of c-myc have been associated with several forms of neoplasia including avian leukosis(More)
5 ABSTRACT.—Little is known about the post-fledging period in most bird species, and almost nothing has been reported for the family Emberizidae, including New World sparrows. We report here, for the first time, the sizes (wing length and body weight) of, and the distances traveled by fledgling Grasshopper Sparrows within their hatch summer in a restored(More)
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