Henriqueta Coimbra

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One of the main mechanisms responsible for MDS molecular pathogenesis involves the activation of tyro-sine-kinase receptors, such as FLT3, RAS proteins, and deregulation of apoptotic pathways. Regarding this, new drugs have been developed to target pathways involved in malignancy, such as Farnesyltransferase Inhibitors (IFTs) and proteasome inhibitors (PI).(More)
I T IS WIDELY known that, unlike other transplants, liver allografts behave as an immunologically favored organ and that their outcome is apparently independent of HLA compatibility, showing a special tolerance status and prolonged survival. 1 It is also known that controling rejection is the most important aspect in the treatment of posttrans-plant(More)
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