Henrique Manoel Lederman

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PURPOSE To retrospectively assess whether computed tomographic (CT) findings can indicate the benign or malignant nature of pulmonary nodules in pediatric patients with malignant solid primary tumors. MATERIALS AND METHODS With institutional review board approval, waived parental and patient consent, and HIPAA compliance, the authors determined the(More)
OBJECTIVES To evaluate and compare demographic, clinical, laboratory and angiographic data of Brazilian children and adolescents with Takayasu's arteritis. METHODS In this Brazilian multicentre, retrospective study which included 10 paediatric rheumatology centres, we identified 71 children and adolescents with Takayasu's arteritis which were diagnosed(More)
The aim of this study is to describe some radiological features in the newborns with microcephaly caused by Zika virus infection during pregnancy. We radiologically analyzed 13 cases of newborns with microcephaly born to mothers who were infected by the Zika virus in the early stage of pregnancy. The most frequently observed radiological findings were(More)
The purpose of this study was to determine whether aerobic plus resistance training (AT + RT) is more effective than aerobic training (AT) at reducing inflammatory markers and cardiovascular risk in obese adolescents. A total of 139 obese adolescents were enrolled, aged 15-19 years, body mass index (BMI) ≥ 95th percentile and participated in 1 year of(More)
Abstract Background. It is essential that we find ways to reduce radiation exposure to children and maintain image quality. Objectives. We compared radiation dose, image quality, and spatial resolution when continuous and pulse fluoroscopy with a full and half dose are applied to a phantom. The film-screen technique was compared to fluoroscopy with the(More)
This study analyzed the intratumoral activity of interferon alpha (IFN-α) in the treatment of cystic craniopharyngiomas. From January 2000 to January 2004, nine patients presenting with cystic craniopharyngiomas were treated with intratumoral injection of IFN-α at the Pediatric Oncology Institute of the Federal University of São Paulo–Escola Paulista de(More)
BACKGROUND The incidence of nonalcoholic fatty liver disease (NAFLD) is increasing due to its prevalence in obesity, diabetes, and insulin-resistance syndrome. The best treatment protocol for NAFLD has not been determined. However, there is evidence that exercise and nutritional intervention can improve and prevent it. The aim of the present study was to(More)
Background: Tuberous sclerosis (TS) is a neurocutaneous genetically inherited disease with variable penetrance characterized by dysplasias and hamartomas affecting multiple organs. MR is the imaging method of choice to demonstrate structural brain lesions in TS. Objective: To compare MR sequences and determine which is most useful for the demonstration of(More)
OBJECTIVE To describe the ultrasonographic (US) findings in the hips of patients with juvenile idiopathic arthritis (JIA) and the association between these findings and the signs, symptoms, and activity of the disease. MATERIALS AND METHODS The present retrospective study included 92 patients with JIA. The disease subtypes, age at disease onset, length of(More)
BACKGROUND Visceral adiposity is the major risk factor for paediatric nonalcoholic fatty liver disease. AIMS Determine the prevalence of nonalcoholic fatty liver disease according to the visceral fat quartile. SUBJECTS 181 obese adolescents including 113 girls (16.58+/-1.56 years) and 68 boys (16.87+/-1.62 years) were evaluated. METHODS The inclusion(More)