Henrik Almroth

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OBJECTIVE To assess the safety of long-term treatment with flecainide in patients with atrial fibrillation (AF), particularly with regard to sudden cardiac death (SCD) and proarrhythmic events. DESIGN Retrospective, observational cohort study. SETTING Single-centre study at Örebro University Hospital, Sweden. Subjects.  A total of 112 patients with(More)
AIMS To evaluate the effect of atorvastatin in achieving stable sinus rhythm (SR) 30 days after electrical cardioversion (CV) in patients with persistent atrial fibrillation (AF). METHODS AND RESULTS The study included 234 patients. The patients were randomized to treatment with atorvastatin 80 mg daily (n = 118) or placebo (n = 116) in a prospective,(More)
AIMS No large randomized multicentre trial has evaluated the efficacy of radiofrequency ablation (RFA) vs. anti-arrhythmic drug (AAD) therapy as a first-line treatment of paroxysmal atrial fibrillation (AF). METHODS AND RESULTS The Medical ANtiarrhythmic Treatment or Radiofrequency Ablation (MANTRA-PAF) trial is a randomized, controlled, parallel group,(More)
Henrik Almroth was born on a sunny day in August 1970, parented by a psychologist and a teacher as their first offspring. Already at the age of fifteen, he was described as " swift and willing " by Valdemar Andersson, Korsanäs Handelsträdgård, first employer. In 1995, life became more serious, and studies of medicine began. After some 5 years in Linköping,(More)
BACKGROUND The aim of this study was to investigate whether high-sensitivity C-reactive protein (hsCRP) levels prior to cardioversion (CV) predict recurrence of atrial fibrillation (AF) in patients randomized to treatment with either atorvastatin or placebo 30 and 180 days after CV. METHODS This was a prespecified substudy of 128 patients with persistent(More)
A model for physician-led team triage was evaluated at the Emergency Department at the University hospital of Örebro, Sweden. Data from 1600 patients indicate that this work model reduces length of stay, time to physician assessment, emergency department occupancy, rate of admission and the proportion of patients in need of close monitoring. The project was(More)
INTRODUCTION Inflammation, endothelial dysfunction and metabolic pathways provide possible links between the inflammatory and hypofibrinolytic states in atrial fibrillation. Our aim was to explore the role of mass concentrations of PAI-1 and tPA, activities of PAI-1 and tPA as predictors of recurrence of atrial fibrillation adjusted for CRP. MATERIALS AND(More)
Henrik Almroth (2012): Atrial Fibrillation: Inflammatory and pharmacological studies. Background: Atrial fibrillation (AF) is the most common rhythm disorder. Many patients are symptomatic. Anti-arrhythmic pharmacological strategies have poor efficacy and side effects are common. Little information about the safety of anti-arrhythmic treatment, especially(More)
OBJECTIVES Total endoscopic ablation of atrial fibrillation is an alternative to catheter ablation, but its clinical role needs further evaluation. The aim of this study was to compare total endoscopic ablation with rate control in patients with long-standing persistent atrial fibrillation and to examine the effect of endoscopic ablation on heart rhythm,(More)
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