Henrik A. Hartmann

Learn More
1. Der primäre Angriffspunkt der IDPN ist der marklose oder markarme proximale Axonabschnitt der Riesenneuronen des retikulären Systems des Hirnstammes, der Kerne des N. statoacusticus (VIII), der Vorderhörner des Rückenmarks und — zu einem geringeren Grad — einiger Hirnnervenkerne. 2. Die Verteilung der schwersten Schäden deckt sich annähernd mit der(More)
When given to rats, both organic and inorganic mercury compounds were found to be neurotoxic. After CH3HgCl intoxication, focal cytoplasmic degradation was the most characteristic lesion observed in the neurons of the dorsal root ganglion. A large cytoplasmic vacuole was formed in many neurons as a result of such lesions. After HgCl2 poisoning, the dorsal(More)
Methylmercuric chloride (CH3HgCl) or mercuric bichloride (HgCl2) were administered to the rats at a dosage of 1.0 mg/kg body weight. Toluidine blue-albumin was injected into these animals at various periods after the intoxication. Leakage of the dye into the nervous parenchyma was observed as early as 12 h after the intoxication indicating an impairment and(More)
To establish objectively the involvement of neurons in the medulla oblongata in patients with amyotrophic lateral sclerosis (ALS), ribonucleic acid (RNA) content was determined in neurons of the hypoglossal nucleus and the nucleus ambiguus. Neurons from those two nuclei showed a significant loss of RNA content in patients with ALS; only 57% and 38% of the(More)
Developing brine shrimp are a good experimental model for study of gene expression during development. Development is initiated on suspension of brine shrimp cysts in seawater. Only 48 hr are required for progression from cyst to the larval stage. We have localize the alpha- and beta-subunits in different cells by immunostaining as development progresses.(More)
Scenario analysis is a process of evaluating possible future events through the consideration of alternative plausible (though not equally likely) outcomes (scenarios). The analysis is designed to enable improved decision-making and assessment through a more rigorous evaluation of possible outcomes and their implications. For environmental impact assessment(More)
Adult male rats were intoxicated with methylmercuric chloride (CH3HgCl) or mercuric bichloride (HgCl2) at a daily dosage of 1.0 mg/kg body weight for various length of periods. Single neurons were dissected out from the dorsal root ganglia with the aid of a de Fonbrune micromanipulator. The RNA of these neurons was extracted and the base composition of the(More)