Henriette Poaty

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Macroscopic Analysis of Fetus Having Arhinencephaly, Synophthalmia and Holoprosencephaly Henriette Poaty1*, David Gentien2, Cecile Reyes2 and Jacques Silou3 1Laboratory of Histology, Embryology and Genetic Medical Faculty, BP 2672, University Marien Ngouabi, Brazzaville, Congo, Africa 2Plateforme Genomics, Department of Translational Research, 26 rue d’Ulm(More)
Eleven samples of DNA from choriocarcinomas were studied by high resolution CGH-array 244 K. They were studied after histopathological confirmation of the diagnosis, of the androgenic etiology and after a microsatellite marker analysis confirming the absence of contamination of tumor DNA from maternal DNA. Three cell lines, BeWo, JAR, JEG were also studied(More)
The complete hydatidiform mole (CHM), a gestational trophoblastic disease, is usually caused by the development of an androgenic egg whose genome is exclusively paternal. Due to parental imprinting, only trophoblasts develop in the absence of a fetus. CHM are diploid and no abnormal karyotype is observed. It is 46,XX in most cases and less frequently 46,XY.(More)
Abnormal trophoblast differentiation is the main cause of gestational trophoblast diseases in the case of hydatidiform moles and choriocarcinomas. Here we investigated the expression patterns of two gene products, p16 and Bcl-2, implicated in cell cycle regulation and apoptosis, respectively, using immunohistochemistry during normal placenta(More)
BACKGROUND We aimed to investigate the prevalence of Lynch syndrome as one of hereditary causes of colorectal cancer (CRC) among young Congolese individuals affected by the CRC, and to define methods for diagnosis in Congo Brazzaville. METHODS We conducted a transversal cohort study of 34 patients having a CRC with a family history for a period of eight(More)
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