Henri Wallaschofski

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Genetic studies of body mass index yield new insights for obesity biology

Adam E Locke, Bratati Kahali, +478 authors Elizabeth K. Speliotes
Nature
2015

Obesity is heritable and predisposes to many diseases. To understand the genetic basis of obesity better, here we conduct a genome-wide association study and Metabochip meta-analysis of body mass… (More)

Cohort profile: the study of health in Pomerania.

Henry Völzke, Dietrich Alte, +62 authors Wolfgang Hoffmann
International journal of epidemiology
2011

Cohort Profile: The Study of Health in Pomerania Henry Völzke, y Dietrich Alte,1y Carsten Oliver Schmidt, Dörte Radke, Roberto Lorbeer, Nele Friedrich, Nicole Aumann, Katharina Lau, Michael Piontek,… (More)

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

Iris M. Heid, Anne U. Jackson, +297 authors Cecilia M. Lindgren
Nature Genetics
2011

Iris M Heid, Anne U Jackson, Joshua C Randall, Thomas W Winkler, Lu Qi, Valgerdur Steinthorsdottir, Gudmar Thorleifsson, M Carola Zillikens, Elizabeth K Speliotes, Reedik Mägi, Tsegaselassie… (More)

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.

Abbas Dehghan, Josée Dupuis, +111 authors Daniel Chasman
Circulation
2011

BACKGROUND C-reactive protein (CRP) is a heritable marker of chronic inflammation that is strongly associated with cardiovascular disease. We sought to identify genetic variants that are associated… (More)

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

Alexander Teumer, Mathias Gorski, +248 authors Caroline S. Fox
Nature communications
2016

Reduced glomerular filtration rate defines chronic kidney disease and is associated with cardiovascular and all-cause mortality. We conducted a meta-analysis of genome-wide association studies for… (More)

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

Sonja I. Berndt, Stefan Gustafsson, +318 authors Erik Ingelsson
Nature Genetics
2013

Approaches exploiting trait distribution extremes may be used to identify loci associated with common traits, but it is unknown whether these loci are generalizable to the broader population. In a… (More)

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

John Campbell Chambers, Weihua Zhang, +133 authors Jaspal Singh Kooner
Nature Genetics
2011

Concentrations of liver enzymes in plasma are widely used as indicators of liver disease. We carried out a genome-wide association study in 61,089 individuals, identifying 42 loci associated with… (More)

Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways

Eriksson, Bart Cjm Fauser, +146 authors Kathryn L. Lunetta
2012

To identify novel loci for age at natural menopause, we performed a meta-analysis of 22 genomewide association studies in 38,968 women of European descent, with replication in up to 14,435 women. In… (More)

A genome-wide association study of metabolic traits in human urine

Karsten Suhre, Henri Wallaschofski, +21 authors Matthias Nauck
Nature Genetics
2011

We present a genome-wide association study of metabolic traits in human urine, designed to investigate the detoxification capacity of the human body. Using NMR spectroscopy, we tested for… (More)

Operative treatment of prolactinomas: indications and results in a current consecutive series of 212 patients.

Juergen Kreutzer, Rolf Buslei, +4 authors Michael Buchfelder
European journal of endocrinology
2008

OBJECTIVE Medical therapy with dopamine agonists (DA) is the primary treatment of choice in most patients with prolactinomas. 'Classical' surgical indications are intolerance or lack of efficiency of… (More)

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