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A major goal of proteomics is the complete description of the protein interaction network underlying cell physiology. A large number of small scale and, more recently, large-scale experiments have contributed to expanding our understanding of the nature of the interaction network. However, the necessary data integration across experiments is currently(More)
BACKGROUND Today, there is a growing need in bioinformatics to combine available software tools into chains, thus building complex applications from existing single-task tools. To create such workflows, the tools involved have to be able to work with each other's data--therefore, a common set of well-defined data formats is needed. Unfortunately, current(More)
We present four tools for the analysis of RNA secondary structure. They provide animated visualization of multiple structures, prediction of potential conformational switching, structure comparison (including local structure alignment) and prediction of structures potentially containing a certain kind of pseudoknots. All are available via the Bielefeld(More)
This article describes how the service-oriented approach could be adopted to the automation environment. The concept of services could be used to classify services of large, heterogeneous systems. One of the main aspects of services is the dynamic assignment and usage at runtime. Taking this into account, dynamic, flexible and scalable systems could be(More)
supports Internet­based collaborative research and education in bioinformatics. Currently, 29 software tools and various educational media are available. These include tools from BiBiServ Tools Here, we focus on the seven most prominent or recent tools on BiBiServ. REPuter [1] uses efficient algorithms and data structures to locate exact repeats in linear(More)
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