Henk Visser

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INTRODUCTION For patients with rheumatoid arthritis (RA) whose treatment with a tumour necrosis factor inhibitor (TNFi) is failing, several biological treatment options are available. Often, another TNFi or a biological with another mode of action is prescribed. The objective of this study was to compare the effectiveness and cost-effectiveness of three(More)
The thermal distortion of the narrow face mold plates in a funnel-mold caster is explored with numerical simulation and online measurements. A three-dimensional finite-element model of the mold and waterbox with full geometric detail is used to explore the evolution of temperature and distortion of the mold during startup. The thermal boundary conditions(More)
OBJECTIVES To study the number of patients that taper or discontinue concomitant methotrexate (MTX) in daily practice in patients with rheumatoid arthritis (RA) treated with tumour necrosis factor inhibitor (TNFi) and to analyse the effects of that adaption on disease activity and drug survival. METHODS Data were collected from the Dutch Rheumatoid(More)
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