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OBJECTIVE To collect and integrate existing data concerning the occurrence, extent, time course, and prognostic determinants of motor recovery after stroke using a systematic methodologic approach. DATA SOURCES A computer-aided search in bibliographic databases was done of longitudinal cohort studies, original prognostic studies, and randomized controlled(More)
A syndrome of paroxysmal, episodic sympathetic hyperactivity after acquired brain injury has been recognized for almost 60 years. This project sought to simplify the confused nomenclature for the condition (>31 eponyms) and simplify the nine overlapping sets of diagnostic criteria. A consensus-developed questionnaire based on a systematic review of the(More)
Paralysis of the upper extremity is a severe motor impairment that can occur after stroke. Prediction of recovery from paralysis is difficult and is primarily based on subjective clinical evaluation. However, the integrity of the sensorimotor system can be assessed objectively and quantitatively by measuring evoked potentials. In this retrospective(More)
The objective of this study was to use motor evoked potentials (MEPs) to analyze the integrity of fast corticospinal functions as the neurophysiologic basis for motor recovery in stroke patients. This was a cohort study including 44 acute stroke patients with paralysis of the upper or the lower extremity. Motor evoked potentials of the abductor digiti(More)
OBJECTIVE The primary aim of this study was to compare the predictive value of motor evoked potentials (MEPs) and early clinical assessment with regard to long-term hand motor recovery in patients with profound hemiplegia after stroke. METHODS The sample was an inception cohort of 39 stroke patients with an acute, ischemic, supratentorial stroke and an(More)
Transcranial magnetic stimulation (TMS) has been successful in the prediction of motor recovery in acute stroke patients with initially severe paresis or paralysis of the upper extremity. Motor evoked potentials (MEP) appear to have a high specificity but a rather low sensitivity with regard to motor recovery. The silent period (SP) has been proposed as an(More)
We report the case of an intellectually deteriorating 66-year-old man who presented with an epileptic seizure. CT of the brain suggested a low-grade astrocytoma, but MRI showed multiple punctate hemorrhagic lesions and a demyelination of vascular origin. Brain biopsy revealed depositions of amyloid in cortical and meningeal arteries. MRI may be of value in(More)
OBJECTIVE To clarify the prognostic value of motor-evoked potentials (MEPs) in predicting motor and functional outcomes after acute stroke. DATA SOURCES A computer-aided search to identify original prognostic studies published from 1988 through 2000; relevant references cited in the retrieved articles were also included. STUDY SELECTION A preliminary(More)
OBJECTIVE To summarize and critically appraise the available evidence on exercise therapy and other types of physical therapies for patients with neuromuscular diseases (NMD). DATA SOURCES Cochrane Central Register of Controlled Trials and Cochrane Database of Systematic Reviews, Medline, CINAHL, EMBASE (Rehabilitation and Physical Medicine), and(More)
BACKGROUND Dysautonomia after traumatic brain injury (TBI) is characterized by episodes of increased heart rate, respiratory rate, temperature, blood pressure, muscle tone, decorticate or decerebrate posturing, and profuse sweating. This study addresses the incidence of dysautonomia after severe TBI, the clinical variables that are associated with(More)