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Left main coronary artery (LMCA) disease is prevalent, occurring in 4% to 7% of patients undergoing coronary angiography. Several studies have highlighted the inadequacies of coronary angiography in the assessment of intermediate LMCA stenosis, leading to the use of other modalities to determine LMCA stenosis severity. Fractional flow reserve (FFR) is now(More)
Methods Nine hundred seven patients referred to the Catharina Hospital were randomized to SES or BMS, and to abciximab or no abciximab in a prospective, randomized, open 2 2 factorial trial with blinded evaluation. Primary endpoint was major adverse cardiac and cerebrovascular events (MACCE), defined as the composite of death, myocardial infarction (MI),(More)
Background. Severity of coronary artery stenosis has been defined in terms of geometric dimensions, pressure gradient-flow relations, resistance to flow and coronary flow reserve, or maximum flow capacity after maximum arteriolar vasodilation. A direct relation between coronary pressure and flow, however, may only be presumed if the resistances in the(More)
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